Giant lumbar spinal schwannoma: a case report and literature review

Nguyen, Thi Kieu Loan; Vo, Nhu Quynh; Ngo, Dac Hong An; Le, Trong Binh; Nguyen, Thanh Minh; Thanh, Thao Nguyen

doi:10.1016/j.radcr.2021.06.004

Cited by 3 publications

(2 citation statements)

References 18 publications

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“…Spinal schwannomas are the most common nerve sheath tumors of the spine, arising from Schwann cells ( 13 ). The incidence of spinal schwannomas varies with age and the peak incidence is in the fourth and fifth decades of life ( 14 ). They have a complex three-dimensional structure as they grow within the spinal canal.…”

Section: Discussionmentioning

confidence: 99%

Scoring model to predict postoperative neurological deterioration in spinal schwannoma

Liu

Xu²,

Shen³

et al. 2023

Front. Oncol.

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BackgroundSpinal schwannomas (SSs) are benign tumors affecting the nerve sheath, accounting for 25% of spinal nerve root tumors. Surgery represents the mainstay of treatment for SS patients. Following surgery, approximately 30% of patients experienced developed new or worsening neurological deterioration, which probably represented an inevitable complication of nerve sheath tumor surgery. The objective of this study was to identify the rates of new or worsening neurological deterioration in our center and accurately predict the neurological outcomes of patients with SS by developing a new scoring model.MethodsA total of 203 patients were retrospectively enrolled at our center. Risk factors associated with postoperative neurological deterioration were identified by multivariate logistic regression analysis. β–coefficients for independent risk factors were used to define a numerical score to generate a scoring model. The validation cohort at our center was used to verify the accuracy and reliability of the scoring model. Receiver operating characteristic (ROC) curve analysis was used to evaluate the performance of the scoring model.ResultsIn this study, five measured variables were selected for the scoring model: duration of preoperative symptoms (1 point), radiating pain (2 points), tumor size (2 points), tumor site (1 point), and dumbbell tumor (1 point). The scoring model divided the spinal schwannoma patients into three categories: low risk (0-2 points), intermediate risk (3-5 points), and high risk (6-7 points), with predicted risks of neurological deterioration of 8.7%, 36%, and 87.5%, respectively. And the validation cohort confirmed the model with the predicted risks of 8.6%, 46.4%, and 66.6%, respectively.ConclusionThe new scoring model might intuitively and individually predict the risk of neurological deterioration and may aid individualized treatment decision-making for SS patients.

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Section: Discussionmentioning

confidence: 99%

Scoring model to predict postoperative neurological deterioration in spinal schwannoma

Liu

Xu²,

Shen³

et al. 2023

Front. Oncol.

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“…The diagnosis of schwannoma is often late or misdiagnosed with other tumors, especially with Baker's cyst [3]. The large schwannoma is often presented in the spine [4,5], head, and neck (25%-45%) [6], while they represent approximately 5% of soft tissue neoplasm [1]. They rarely occur in the lower extremities, and in the popliteal fossa even more rarely [6,7].…”

Section: Introductionmentioning

confidence: 99%

The Rare Large Common Peroneal Nerve’s Schwannoma—A Case Report and Literature Review

Harahap,

Harahap

2024

Case Reports in Oncological Medicine

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Schwannoma in the popliteal fossa is still rare, often diagnosed late because it grows slowly and has no symptoms. It is often misdiagnosed with connective tissue tumors or with neurological disorders originating in the spine or disorders of the peroneal nerve. Schwannoma within the common peroneal nerve is still rare in the popliteal fossa, with most tumor sizes around 2 cm in diameter due to their smaller size of nerve but can cause neurologic disturbance, especially when it is large. And over a long time, it can cause serious complaints like neurological deficits and make surgery difficult by leaving greater sequelae. There is no data yet showing the incidence of schwannoma in the common peroneal nerve. In this case, a 36-year-old woman, for 5 years, feels soreness in the popliteal fossa and pain in the right instep, suspected that a nerve was pinched, due to an abnormality in the spine. As time went on, there was a lump in the fold of the right knee, suspected to be a Baker’s cyst. As time went by, the complaint was burning pain in the right instep to the lateral ankle and distal right lower leg, disturbing sleep. Tinel’s sign was positive. The right instep has hypoesthesia and a slight drop in the foot. On radiological examination of the right knee, a circumferential mass appeared, measuring 5 cm×4 cm. The diagnosis is suspicious for a common peroneal nerve tumor. The encapsulated operation to remove the tumor was carried out with a size measuring 5 cm×4.5 cm×4 cm. The histopathological examination showed schwannoma. After surgery, the pain disappeared, hypoesthesia and a slight drop in the foot underwent physiotherapy, and stimulation with the result gradually improved. A thorough early examination includes correct and systematic anamnesis, physical examination, and neurological evaluation such as paraesthesia, hypoesthesia, and Tinel’s sign; also, additional examinations, such as radiographic, ultrasound, and MRI, are needed for early detection of schwannoma so that delays in diagnosis and surgery can be avoided to prevent neurological deficits.

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Giant cystic Intradural extramedullary tumor of the lumbar spine mimicking arachnoid cyst: A case report

Nazwar,

Bal'afif,

Wardhana

et al. 2024

International Journal of Surgery Case Reports

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Giant lumbar spinal schwannoma: a case report and literature review

Cited by 3 publications

References 18 publications

Scoring model to predict postoperative neurological deterioration in spinal schwannoma

Scoring model to predict postoperative neurological deterioration in spinal schwannoma

The Rare Large Common Peroneal Nerve’s Schwannoma—A Case Report and Literature Review

Giant cystic Intradural extramedullary tumor of the lumbar spine mimicking arachnoid cyst: A case report

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