Giant myxoid liposarcoma of the stomach: Report of a case

Sonoda, Akari; Shinmoto, Hiroshi; Miyanari, Nobutomo; Mizumoto, Takao; Kubota, Tatsuo; Baba, Hideo

doi:10.1016/j.ijscr.2019.06.025

Cited by 10 publications

(8 citation statements)

References 17 publications

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“…The follow-up period described in the above cases varied from 2 months to 72 months. None of the patients had a known relapse of the disease, and only one patient died from heart infarction 13 months after surgery [ 9 – 11 ].…”

Section: Discussionmentioning

confidence: 99%

“…Conversely, liposarcomas are one of the most common soft-tissue sarcomas, usually affecting the limbs, retroperitoneum, and trunk [7]. Gastric liposarcomas are extremely rare, and mere 39 cases have been reported worldwide, with the antrum being the main location [8,9]. Although GISTs quite often (in up to 38% of cases) coexist with other primary tumors [10], only three cases of synchronous GIST and intra-abdominal liposarcoma have been reported in the literature [11][12][13].…”

Section: Introductionmentioning

confidence: 99%

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Gastrointestinal Stromal Tumor (GIST) and Synchronous Intra-Abdominal Liposarcoma: A Report of Two Rare Cases and Literature Review

Samara

Baloyiannis

Symeonidis

et al. 2021

International Journal of Surgical Oncology

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Introduction. Gastrointestinal stromal tumors (GISTs) quite frequently occur synchronously with other malignancies, with most cases being adenocarcinomas. GISTs and liposarcomas are both of mesenchymal origin, and their coexistence is extremely rare. Methods. We conducted a review of the current literature regarding the synchronous occurrence of GISTs and intra-abdominal liposarcomas. An electronic search of the literature was undertaken using MEDLINE (database provider PubMed). Furthermore, we present the first described case of an 86-year-old male with a GIST and synchronous liposarcoma, both located in the stomach, as well as a 66-year-old male with a gastric GIST and concurrent retroperitoneal liposarcoma. Results. A total of 5 cases of synchronous GIST and intra-abdominal liposarcoma have been reported in the literature to date, with the most recent cases included in the present study. Conclusion. Further research is required to explain any possible correlation in the coexistence of these different neoplasms of the same origin. Meanwhile, R0 resection of both tumors remains the treatment of choice.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Gastrointestinal Stromal Tumor (GIST) and Synchronous Intra-Abdominal Liposarcoma: A Report of Two Rare Cases and Literature Review

Samara

Baloyiannis

Symeonidis

et al. 2021

International Journal of Surgical Oncology

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“…Although DDPLS and WDLPS are the most common subtypes of liposarcomas described in the GI tract, a few case reports also described the exceptional occurrence of myxoid liposarcomas (MLPS) 65 , 66 . Myxoid liposarcoma is composed of cytologically bland spindle to ovoid cells associated with monovacuolated lipoblasts, set in a myxoid stroma with prominent plexiform capillary network.…”

Section: Neoplasm With Adipocytic Differentiationmentioning

confidence: 99%

Mesenchymal tumours of the gastrointestinal tract

et al. 2021

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Summary Mesenchymal tumours represent a heterogenous group of neoplasms encopassing benign, intermediate malignancy, and malignant entities. Sarcomas account for approximately 1% of human malignancies. In consideration of their rarity as well as of intrinsic complexity, diagnostic accuracy represents a major challenge. Traditionally, mesenchymal tumours are regarded as lesions the occurrence of which is mostly limited to somatic soft tissues. However, the occurrence of soft tissue tumours at visceral sites represent a well recognized event, and the GI-tract ranks among the most frequently involved visceral location. There exist entities such as gastrointestinal stromal tumours (GIST) and malignant gastointestinal neuroectodermal tumors that exhibit exquisite tropism for the GI-tract. This review will focus also on other relevant clinico-pathologic entities in which occurrence at visceral location is not at all negligible.

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“…[ 1 , 2 ]. Although it occurs predominantly in the deep soft tissues of the extremities, LPS is also reported in the abdomen in areas such as the esophagus, stomach, and descending mesocolon [ 3 , 4 ]. The retroperitoneum is a rare LPS location, with only a few publications discussing its diagnosis, clinical characteristics, and prognosis [ 2 , 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Diagnosis and Prognosis of Retroperitoneal Liposarcoma: A Single Asian Center Cohort of 57 Cases

Xiao

Liu

Chen

et al. 2021

Journal of Oncology

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Background. Liposarcoma is a soft tissue malignancy, commonly observed in the extremities. However, retroperitoneal liposarcoma is seldom reported and its diagnosis is frequently neglected. This study aims to present the clinical characteristics, diagnosis, and prognosis of five liposarcoma subtypes and report our experience of patient treatment. Methods. We conducted a single-center noninterventional retrospective study of 57 retroperitoneal liposarcoma patients admitted to Peking Union Medical College Hospital (PUMCH, Beijing, China) between July 2011 and December 2019. We collected and analyzed their demographic, clinical, imaging, histological, therapeutic, and prognostic data over a mean 4.5-year follow-up period. Results. Twenty-five (44%) patients were asymptomatic prior to diagnosis, with abdominal distension as the chief complaint in 18 (32%) patients and abdominal pain observed in 16 (28%) patients. Masses were evaluated by computed tomography (n = 48, 84%) or ultrasound (n = 25, 44%). Laparotomy (n = 52, 91%) was the dominant therapeutic modality rather than laparoscopy (n = 5, 9%). All patients were treated with R0 resection except two patients who underwent R2 resection. We conducted regular follow-ups every six months after surgery for a mean duration of 4.5 years. Recurrence was experienced by 14 (25%) patients and a further 9 (16%) died during follow-up. Conclusions. Abdominal distension and pain are chief complaints with liposarcoma. As the extremities are the main liposarcomas locations, the diagnosis of retroperitoneal liposarcoma is usually neglected. Since half of the patients are asymptomatic, timely diagnosis and treatment are highly dependent on regular ultrasound and computed tomography imaging. R0 resection is the key to retroperitoneal liposarcoma treatment. In comparison, patients who underwent R2 resection, which is considered a palliative treatment, had bad prognoses. Large, symptomatic dedifferentiated, and pleomorphic liposarcomas are more likely to have poor prognoses, while the prognosis for well-differentiated or myxoid liposarcoma is relatively good.

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Giant myxoid liposarcoma of the stomach: Report of a case

Cited by 10 publications

References 17 publications

Gastrointestinal Stromal Tumor (GIST) and Synchronous Intra-Abdominal Liposarcoma: A Report of Two Rare Cases and Literature Review

Gastrointestinal Stromal Tumor (GIST) and Synchronous Intra-Abdominal Liposarcoma: A Report of Two Rare Cases and Literature Review

Mesenchymal tumours of the gastrointestinal tract

Diagnosis and Prognosis of Retroperitoneal Liposarcoma: A Single Asian Center Cohort of 57 Cases

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