TOPIC: Study on self-effi cacy and its related factors in elderly patients with intestinal stoma. PURPOSE: To describe the current situation and relationship of Self-Effi cacy, Perceived Control, and Self-Perceived Burden (SPB) in elderly patients with stoma. Try to analyze the infl uencing and promoting factors of Self-Effi cacy. METHODS: Th e researchers investigated 349 elderly patients (mean age: 70.34 ± 7.66 years [mean ± SD]) with SSES, Perceived Control in Health Care Questionnaire, and SPB. Th e researchers also interviewed 14 patients (mean age: 72.07 ± 8.89 years) face-to-face and semistructured to understand their feelings and experiences and fi nally to obtain the promoting factors of Self-Effi cacy. RESULTS: Th e score of SSES was (77.07 ± 21.47). Th e vast majority are in the middle level (64.01%). Th e education, residence, persistent time of stoma, and self-care were signifi cantly related to Self-Effi cacy ( P < .05). Th ere was a positive correlation between perceived control and self-effi cacy ( r = 0.519, P < .05) and a negative correlation between SPB and Self-Effi cacy ( r = 0.432, P < .05). In the multiple regression analysis, all the variables entering the model explained 56.9% of Self-Effi cacy. Th e analysis of intermediary eff ect suggests that Perceived Control played a completely mediating role in the prediction of SPB and Self-Effi cacy and had a signifi cant predictive eff ect ( β = − .606, P < .05). Four themes are obtained by IPA analysis: Self-Care, Living Habits, Depression, and Benefi ts Found. Th e promote factors involve objective factors (adequate disease awareness and abundant support systems) and internal factors (appropriate rehabilitation expectations and positive coping strategy). CONCLUSION: Perceived Control and SPB can aff ect the level of Self-Effi cacy. In clinical practice, patients' needs for disease-related knowledge and social support should be met, patients should be encouraged to participate in colostomy management, and patients should be guided to adopt positive coping strategies to help patients improve their self-effi cacy.