1979
DOI: 10.1001/archopht.1979.01020010450011
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Giant Papillary Conjunctivitis With Ocular Prostheses

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Cited by 75 publications
(24 citation statements)
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“…The symptoms of GPC (excess mucus production and itching) usually come before papillary conjunctivitis is observed, and there is a poor correlation between symptoms and observed enlarged papillae. Studies of GPC associated with prosthetic eye wear have concluded that prolonged wear of prosthetic eyes is associated with GPC [ 23 ] and that GPC is an allergic disease of the eye associated with increased numbers of mast cells, eosinophils and lymphocytes in the conjunctiva [ 24 ]. The signs of GPC are most apparent on the upper tarsal conjunctiva but can be observed on the lower tarsal conjunctiva which is easier to access.…”
Section: Volume Of Dischargesupporting
confidence: 39%
“…The symptoms of GPC (excess mucus production and itching) usually come before papillary conjunctivitis is observed, and there is a poor correlation between symptoms and observed enlarged papillae. Studies of GPC associated with prosthetic eye wear have concluded that prolonged wear of prosthetic eyes is associated with GPC [ 23 ] and that GPC is an allergic disease of the eye associated with increased numbers of mast cells, eosinophils and lymphocytes in the conjunctiva [ 24 ]. The signs of GPC are most apparent on the upper tarsal conjunctiva but can be observed on the lower tarsal conjunctiva which is easier to access.…”
Section: Volume Of Dischargesupporting
confidence: 39%
“…Although the presence of small papillae on the upper tarsal conjunctiva may be found in healthy persons [1][2][3], papillogenesis has been reported in contact lens wearers [2,4], wearers of prostheses [2,[5][6][7], and postoperatively from exposed and loose sutures after cataract extraction [5,[8][9][10] and keratoplasty [11][12][13], It was originally proposed that the development of papillae in the case of the giant papillary conjunctivitis syndrome may be a nonspecific response of the upper tarsal conjunctiva [5,14]. Both immunologic and mechanical components may be interrelated in the pathogenesis of giant papillary con junctivitis [15].…”
Section: Introductionsupporting
confidence: 42%
“…No grupo I, constituído de pacientes que têm órbita com olho e não-irradiada, observou-se infiltrado com predomínio de PMNs neutrófilos; e já foi visto que essas são as células mais freqüentes no raspado conjuntival de pacientes normais, embora em pequena quantidade (1,9) . O uso de prótese ocular pode estar associado ao desenvolvimento de conjuntivite papilar gigante (13)(14) . Embora a maioria dos pacientes fosse usuária de prótese ocular, o fato de terem sido observados poucos eosinófilos neste estudo pode estar relacionado ao tempo de uso da prótese inferior a 4 anos (13) .…”
Section: Discussionunclassified
“…O uso de prótese ocular pode estar associado ao desenvolvimento de conjuntivite papilar gigante (13)(14) . Embora a maioria dos pacientes fosse usuária de prótese ocular, o fato de terem sido observados poucos eosinófilos neste estudo pode estar relacionado ao tempo de uso da prótese inferior a 4 anos (13) . As alterações celulares induzidas pela radiação são mais evidentes no primeiro ano pós-tratamento (6) , principalmente nos primeiros seis meses (15) .…”
Section: Discussionunclassified