Giant Pilomatrixoma of the Scrotum: A Rare Case Presentation

Abstract

Pilomatrixoma is a benign adnexal skin tumor involving the hair follicle matrix. It is found in children, predominantly involving the face. We report here an interesting and rare case of a 52-year-old male presenting with a large, firm, and painless mass over the scrotum considered to be a sebaceous cyst. The mass was completely excised and a biopsy report revealed it to be a pilomatrixoma of the scrotum. The patient recovered well postoperatively with no recurrence over two years.

Multiple giant pilomatricomas of the scrotal: A rare case report from Syria

“…A case reported by Adhikari G and Jadhav GS [ 5 ] presented a giant pilomatrixoma. The lesion manifests as a large, firm, non-tender, pear-shaped sessile mass with irregular margins and a lobulated appearance.…”

Calcifying epithelioma of Malherbe – a rare localization

“…Additionally, immunohistochemistry investigations linked pilomatricoma and proto-oncogene B-cell lymphoma antigen 2 overexpression. Foreign bodies, giant-cell tumours, epidermal cysts, dermoid cysts, sebaceous adenoma or carcinoma, calcified lymphadenopathy, ossified or calcified haematoma, and lipomas should all be ruled out as differential diagnoses [4]. Radiological modalities such as ultrasound, MRI, and CT scans play a minimal role in the diagnosis.…”

“…Because it is readily available, ultrasonography is usually appropriate, with a positive predictive value of 95.5%. It can show the mass's superficial location, continuity with deeper structures, and degree of calcification [4]. Thus, definitive diagnosis of the tumour is only acquired through histopathological examination.…”

“…Standard treatment for pilomatricoma is surgical excision with 5-10 mm safety margins. Recently, Mohs micrographic surgery had been employed, especially in situations of suspected malignancy, to assure full margin-free excision [4]. This procedure leads to a low recurrence rate.…”

“…It is frequently encountered in the paediatric age group and particularly affects women with a sex ratio of 1.5 [3]. It mainly represents as a solitary, firm, and subcutaneous mass with an overall incidence rate of 1 in 800 cutaneous tumour [4]. Many cases have been documented regarding the tumour arising from a common location such as the face (preauricular, periorbital), neck, upper limbs, and trunk.…”