Giant premacular bursa: a novel finding of the posterior vitreous in two patients with Stickler syndrome type 1 revealed by swept-source optical coherence tomography

Chen, Kevin C.; Jung, Jesse J.; Engelbert, Michael

doi:10.1007/s00417-015-3125-9

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Cited by 4 publications

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“…Therefore, it is speculated that there may be a relationship between the vitreous liquefaction associated with collagen abnormalities and PPVP dysplasia. Chen et al reported giant premacular bursas (i.e., giant PPVPs) in two cases of Stickler syndrome [ 9 ]. As we have previously reported, the PPVP appeared as a narrow liquefied space in front of the fovea at age three.…”

Section: Discussionmentioning

confidence: 99%

Posterior Precortical Vitreous Pocket in Stickler Syndrome: A Report of Two Cases

Nagashima,

Akiyama,

Nakamura

et al. 2024

Cureus

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Stickler syndrome is a genetic disorder characterized by collagen abnormalities leading to various ocular manifestations, such as retinal detachment. We present two cases of siblings clinically diagnosed with Stickler syndrome who exhibited retinal detachment. Case 1, a seven-year-old girl, and case 2, her 14-yearold brother, both displayed severe myopia and other clinical signs consistent with Stickler syndrome. Despite their ages, neither case showed evidence of posterior precortical vitreous pocket (PPVP) on imaging or during surgical intervention. These findings suggest a potential relationship between collagen abnormalities and PPVP dysplasia in Stickler syndrome.

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Section: Discussionmentioning

confidence: 99%