Giant schwannoma on the lower leg: A case report and review of the literature

Quang, Vinh Pham; Quoc, Huy Hoang; Nguyen, Bach; Quang, Chuong Ngo; Nguyen, Hieu Pham Trung; Nguyen, Ngoc Cuong

doi:10.1016/j.ijscr.2023.108468

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…Although schwannomas may present anywhere, their incidence in the lower limbs is reported in only 1% of cases [7]. Radiographically, conventional schwannomas display iso-or hypo-signal intensity on T1, hyperintensity on T2, and postcontrast enhancement.…”

Section: Discussionmentioning

confidence: 99%

Ancient Schwannoma of the Thigh: Metaplastic Ossification, Cartilage Formation, and Extensive Calcification

Korytkowski,

Kravtsov,

Hariri

et al. 2024

Cureus

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Benign soft tissue masses that present with atypical features on imaging may erroneously be diagnosed as malignant processes. An ancient schwannoma, a schwannoma variant with pronounced degenerative features, is one possible etiology of an incidental soft tissue tumor. This case report describes a 69-year-old male with a history of lung carcinosarcoma who presented to the orthopedic oncology office following an incidental positron emission tomography-computed tomography (PET-CT) finding of a posterior, lateral thigh mass with extensive calcifications. Subsequent excision and pathological analysis revealed an ancient schwannoma with advanced degenerative features, including metaplastic bone and cartilage formation. Various degenerative changes may typically be identified with pathological analysis. In addition to the degenerative findings on pathological analysis, our case highlights an atypical instance where extensive calcification and ossification are evident radiographically. This case emphasizes the importance of considering ancient schwannoma when a calcified soft tissue mass is encountered, in addition to the list of more common calcified soft tissue masses.

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Section: Discussionmentioning

confidence: 99%

Ancient Schwannoma of the Thigh: Metaplastic Ossification, Cartilage Formation, and Extensive Calcification

Korytkowski,

Kravtsov,

Hariri

et al. 2024

Cureus

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Schwannoma of the Lower Limb: A Case Report

Kutalia,

Bolkvadze,

Erdem

2024

Cureus

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Schwannoma is a benign tumor of the peripheral nerve sheath and is a unique clinical entity when localized to a lower limb. Growing as a painless nodule, it might be misdiagnosed by many medical professionals as another benign soft tissue skin condition, such as lipoma, myxoma, or ganglion cyst. Definitive diagnosis of peripheral schwannoma is made by biopsy and histopathologic evaluation, followed by surgical excision, which is the definitive treatment of the tumor. Classic symptoms of schwannoma of the lower limb are peripheral neuropathy (tingling, burning sensations) and motor impairment (weakness, paralysis of the affected limb). MRI imaging and biopsy are the most useful diagnostic methods for peripheral schwannoma, followed by surgical excision, which is the treatment of choice. Postoperative complications, if present, are minimal and rare. Because of the slow-growing nature of the tumor and the complexity of the lower limb's nervous and structural network, it is often asymptomatic and is challenging to diagnose at a primary stage. That is why we want to spread awareness and draw the reader's attention to this rare case of a patient with schwannoma on the left lower limb.

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Giant schwannoma on the lower leg: A case report and review of the literature

Cited by 2 publications

References 19 publications

Ancient Schwannoma of the Thigh: Metaplastic Ossification, Cartilage Formation, and Extensive Calcification

Ancient Schwannoma of the Thigh: Metaplastic Ossification, Cartilage Formation, and Extensive Calcification

Schwannoma of the Lower Limb: A Case Report

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