Giant scrotal lipoma in Madelung's disease: A case report

Dung, Phạm Thị Việt; Sơn, Trần Thiết; Son, Truong Quoc; Tuan, Nguyen Minh

doi:10.1016/j.ijscr.2023.108151

Cited by 4 publications

(1 citation statement)

References 14 publications

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“…Described in 1888 by Otto Madelung, it is a rare disorder of fat metabolism that results in unusual subcutaneous deposits of adipose tissue [ 10 ]. There have been several reports of Madelung's disease lesions confined to the male genital area [ 11 , 12 ] but none in the vulva. The differences between Madelung's disease and bilateral lipomas are not clear, but some sex-related morphologic features have been described, including a “buffalo hump” or “horse collar” in men and a “football player appearance” in women.…”

Section: Discussionmentioning

confidence: 99%

En bloc resection of a large bilateral vulvar lipoma through a caesarean scar: A case report

Hihara,

Fukui,

Mitsui

et al. 2024

Case Reports in Women's Health

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Section: Discussionmentioning

confidence: 99%

En bloc resection of a large bilateral vulvar lipoma through a caesarean scar: A case report

Hihara,

Fukui,

Mitsui

et al. 2024

Case Reports in Women's Health

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Primary scrotal lipoma in a pediatric patient: a case report with current literature review

Hussein,

Bapir,

Ali

et al. 2023

Afr J Urol

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Backgrounds Primary scrotal lipomas are benign fatty tumors that develop from adipocytes of the scrotum. The exact cause of their development is unknown. They are typically painless and may exhibit symptoms of heaviness and discomfort. Case presentation A 9-year-old boy presented with a painless scrotal mass that had been present since birth. The mass was located in the left hemiscrotum. Ultrasound showed an enlarged left testicle with an abnormal outline and heterogeneous texture. Magnetic resonance imaging demonstrated a mass arising from the left hemiscrotum with no invasion of the testis. Under general anesthesia and through a scrotal incision, the mass was excised. Histopathological examination revealed a lipoma. Conclusion Primary scrotal lipomas are benign lesions with an unclear pathogenesis. They are very uncommon in the pediatric age group. Ultrasound is the first-line modality for diagnosing lipomas; however, it may provide ambiguity. MRI provides a more accurate assessment of the mass. Surgical excision of the mass is the standard treatment for primary scrotal lipomas.

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Madelung disease with postoperative priapism and multiple venous thromboses: case report and literature review

Guo,

Li,

et al. 2024

Front. Cardiovasc. Med.

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Madelung disease is an uncommon metabolic disorder of uncertain pathogenesis, distinguished by the symmetric accumulation of nonencapsulated adipose tissue within the subcutaneous layer of the neck, abdomen, thighs, and other anatomical regions. This condition has been tightly connected with comorbidities including diabetes, dyslipidemia, hyperuricemia, hypothyroidism, and adrenal dysfunction, as well as sensory, motor, and autonomic polyneuropathy. The prevalence of Madelung disease is conspicuously higher in Mediterranean and Eastern European, with a distinct scarcity within the Asian population. Surgical interventions involving lipectomy and liposuction represent the foremost and most efficacious treatment approach. Herein, we present a case encompassing type II Madelung disease featuring bilateral thighs adipose tissue accumulation. The patient exhibited unexplained priapism alongside multiple venous thrombosis during four surgical interventions. The infrequent manifestation of postoperative hypercoagulability in patients of Madelung disease merits broad attention, owing to the potentiality for extensive venous thrombosis and consequential severe outcomes such as pulmonary embolism or cerebral infarction arising from thrombus dislodgment. Building upon this clinical scenario, we systematically documented the clinical manifestations and disease progression in this patient, meticulously analyzed the causes of complications, and proposed targeted preventive measures. Additionally, we conducted a comprehensive review of the relevant literature to summarize the clinical and epidemiological features of Madelung disease and to elucidate its mechanisms. This study will provide a valuable reference for future clinical treatments and mitigate perioperative complications of Madelung disease.

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Giant scrotal lipoma in Madelung's disease: A case report

Cited by 4 publications

References 14 publications

En bloc resection of a large bilateral vulvar lipoma through a caesarean scar: A case report

En bloc resection of a large bilateral vulvar lipoma through a caesarean scar: A case report

Primary scrotal lipoma in a pediatric patient: a case report with current literature review

Madelung disease with postoperative priapism and multiple venous thromboses: case report and literature review

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