Giant solitary fibrous tumour breast: a case report

Abstract

Although giant solitary fibrous tumor is a rare soft tissue tumor but is to be considered in the differential diagnosis of benign breast tumors like fibroadenoma and phyllodes tumor at the time of clinical evaluation.

Synthesis of Isoquinolines and Related Heterocycles under Visible-Light Conditions

“…R f = 0.13 (SiO 2 , cyclohexane/ethyl acetate (93:7, v/v)); 1 H NMR (CDCl 3 , 400 MHz, 298.0 K): δ (ppm) 9.21 (s, 1H), 7.94 (d, J = 8.1 Hz, 1H), 7.75 (d, J = 8.2 Hz, 1H), 7.66 (ddd, J = 8.2, 6.8, 1.3 Hz, 1H), 7.53 (ddd, J = 8.2, 6.8, 1.3 Hz, 1H), 7.49 (s, 1H), 2.93 (t, J = 7.7 Hz, 2H), 1.85 (h, J = 7.4 Hz, 2H), 1.00 (t, J = 7.4 Hz, 3H); 13 Spectral data were consistent with data reported in the literature. 31 3-Hexylisoquinoline (2b). After purification by column chromatography on a silica gel (cyclohexane/ethyl acetate (30:1, v/v)), 2b was obtained as a yellow oil in 63% yield (13.5 mg, 0.06 mmol), following general procedure C, starting from (E)-2-(oct-1-yn-1yl)benzaldehyde o-(2,4-dinitrophenyl)oxime 1b (38.9 mg, 0.1 mmol).…”

“…9 Some limitations such as harsh reaction conditions or poor functional group tolerance led chemists to develop new protocols. Thus, isoquinolines' synthesis has then been largely developed with the use of transition metals such as palladium, 10−19 nickel, 20 rhodium, 21−30 gold, 31,32 or silver. 33 However, global warming effect and depletion of such metals lead us to develop greener methods.…”

Rarest of the Rare – Malignant Solitary Fibrous Tumour of the Breast: Case Report and Literature Review

“…Breast SFT is rather unique, with less than 50 cases reported in the literature worldwide. In India, till date only one case of breast SFT was reported, which was benign (5). Malignant SFT of the breast is extremely rare, with only six cases worldwide (6)(7)(8)(9)(10)(11).…”