Giant Splenic Lymphangiomatosis in Adult: a Diagnostic Dilemma

Abstract

Cystic lymphangiomatosis of the spleen occurs secondary to developmental malformation of the lymphatic system. It is one of the rare entities generally seen in children. It is usually seen in children. We report a case of cystic lymphangiomatosis of the spleen occurring in an adult woman presenting with massive splenomegaly. Total splenectomy was considered to be the treatment of choice for making definitive diagnosis and to exclude the presence of malignancy or other causes of massive splenomegaly

Synthesis of 5- [(11substitutedphenothiazinoacetyl) semicarbazidothio- semicarbazido]-2- oxo/thiobarbiuric Acid as Anticonvulsant Agents

“…All the newly synthesized compounds were evaluated for their anticonvulsant activity and acute toxicity studies. 2 ), which confirms the structure of compound 2c. Compounds (2a-2d) were then underwent mannich reaction to yield compounds 3a-3d.…”

“…10H-Phenothiazine nucleus has gained prominance due to its diverse activities like-anticonvulsant, [1][2][3][4][5][6] antinflammatory 7 and cardiovascular 8 . The introduction of various heterocyclic / aliphatic moieties at 10-position of phenothiazine led to the discovery of promethazine [10-(2-methylaminopropyl) phenothiazine hydrochloride].…”

One-pot rapid synthesis of thiazole-substituted pyrazolyl-4-thiazolidinones mediated by diisopropylethylammonium acetate

“…Aromatic amines having halide groups reacted smoothly, and the products were obtained in excellent yields ranging from 79 to 88 % ( Table 5, entries [3][4][5][8][9][10]. Slightly moderate yields of the product were obtained when heterocyclic aldehydes were allowed to react with aromatic amines having electron-donating group such as CH 3 (Table 5, entries 2, 7).…”

“…The media used for the condensation are volatile organic solvents such as toluene, benzene, 1,4-dioxane and tetrahydrofuran (THF). There are reports of acceleration of the above cyclocondensation using catalysts and desiccants such as N,N 0 -dicyclohexylcarbodiimide (DCC) [5], O-(benzotriazolyl)-N,N,N 0 ,N 0 -tetramethyluronium hexafluorophosphate (HBTU) [6], ferrite [7], ZnCl 2 [8], sodium sulphate [9], [bmim][PF 6 ] [10,11] and activated fly ash [12]. Use of microwave heating [13], and solid-phase [14] and polymer-supported [15] systems to run the cyclocondensation leading to 2,3-disubstituted 4-thiazolidinones has also been reported.…”

“…Electron-donating group such as OCH 3 , CH 3 and OH present in the aldehyde afforded moderate yields of the products (Table 4, entries[4][5][6][7][8][9][10][11][12]. Presence of Cl group in the aldehydes (Table 4, entries 13-15) showed good effect on yield.…”