Giardiasis

Minetti, Corrado; Chalmers, Rachel M.; Beeching, Nicholas J.; Probert, Chris; Lamden, Kenneth

doi:10.1136/bmj.i5369

Cited by 73 publications

(73 citation statements)

References 37 publications

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“…Although there have also been studies in which this association was not found , the bulk of the evidence seems to suggest a link between symptomatic or asymptomatic Giardia infection and reduced linear growth in most low‐income contexts. Such an association is likely to be causal, as Giardia infections are often chronic and can lead to prolonged aberrations in gut function and nutrient absorption . Additionally, systemic inflammation caused by chronic infections can interfere the growth hormone – insulin‐like growth factor 1 pathway and reduce growth plate activity and hence linear growth .…”

Section: Discussionmentioning

confidence: 99%

Presence of Giardia lamblia in stools of six‐ to 18‐month old asymptomatic Malawians is associated with children's growth failure

et al. 2019

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Aim Despite high pathogen burden and malnutrition in low‐income settings, knowledge on relationship between asymptomatic viral or parasitic infections, nutrition and growth is insufficient. We studied these relationships in a cohort of six‐month‐old Malawian infants. Methods As part of a nutrient supplementation trial for 12 months, we documented disease symptoms of 840 participant daily and anthropometric measurements every three months. Stool specimens were collected every six months and analysed for Giardia lamblia, Cryptosporidium species and enterovirus, rotavirus, norovirus, parechovirus and rhinovirus using polymerase chain reaction (PCR). The prevalence of the microbes was compared to the children's linear growth and the dietary. Results The prevalence of the microbes was similar in every intervention group. All age groups combined, children negative for G. lamblia had a mean standard deviation (SD) of −0.01 (0.49) change in length‐for‐age Z‐score (LAZ), compared to −0.12 (0.045) among G. lamblia positive children (difference −0.10, 95% CI −0.21 to −0.00, p = 0.047). The LAZ change difference was also statistically significant (p = 0.042) at age of 18–21 months but not at the other time points. Conclusion Asymptomatic G. lamblia infection was mainly associated with growth reduction in certain three‐month periods. The result refers to the chronic nature of G. lamblia infection.

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Section: Discussionmentioning

confidence: 99%

Presence of Giardia lamblia in stools of six‐ to 18‐month old asymptomatic Malawians is associated with children's growth failure

et al. 2019

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“…One small study reported false positives by EIA compared to PCR 10 . The relative sensitivity of methods may be dependent on sample preparation and the assay used 11 .…”

Section: Giardia Intestinalis (Synonymous With Giardia Duodenalis Andmentioning

confidence: 99%

Evaluation of the BD MAX Enteric Parasite Panel for the detection of Cryptosporidium parvum/hominis, Giardia duodenalis and Entamoeba histolytica

Perry

Corden

White

2017

Journal of Medical Microbiology

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“…In a study that focused on the geographic variation of T. gondii strains, most genotypes of the parasite were detected as locale specific, but some were found conserved across continents and closely related to one other, indicating a recent radiation of a pandemic genotype (390). In Turkey, the seroprevalence of T. gondii was detected as 43% in domestic cats (391) Giardiasis is one of the most common zoonotic intestinal protozoan diseases caused by Giardia spp in the Giardiinae subfamily and occurs in humans and animals worldwide, particularly in developing countries; WHO has classified this infection as a neglected disease (400). One species in Giardia genus Giardia duodenalis (syn.…”

Section: Zoonotic Parasitic Protozoans (Protozooses)mentioning

confidence: 99%

Overview of Zoonotic Diseases in Turkey: The One Health Concept and Future Threats

İncı¹,

Doğanay²,

Özdarendeli³

et al. 2018

TurkiyeParazitolDerg

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Zoonotic infections are globally important diseases and lead to huge economic losses in both low-and middle-income and high-income countries. Global warming, environmental and ecological changes, illegal movement of animals and humans, regional civil wars, and poverty are predisposing factors for the emergence of zoonotic infections and their distribution worldwide; they are also a big threat for the future. In addition, environmental pollution and antimicrobial resistance are immense serious threats and dangers to prevent and control zoonotic infections. The natural location of Turkey allows many emerged or re-emerged infections with zoonotic characteristics by animal movements, such as bird immigrations, and by human movements due to civil wars as seen with regional refugees. Numerous zoonotic diseases, including 37 bacterial, 13 fungal, 29 viral, 28 parasitic (3 trematodes, 7 cestodes, 10 nematodes, and 8 protozoan), and totally 107 infections, have been reported from Turkey to date. Additionally, many ectoparasitic zoonoses within 15 different arthropod groups and one leech infestation have been reported from Turkey to date. The "One Health" initiative is particularly relevant for developing strategies to combat zoonotic diseases. In this article, we review the occurrence of zoonotic diseases in man and animals in Turkey in the light of the "One Health" perspective.

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Giardiasis

Cited by 73 publications

References 37 publications

Presence of Giardia lamblia in stools of six‐ to 18‐month old asymptomatic Malawians is associated with children's growth failure

Presence of Giardia lamblia in stools of six‐ to 18‐month old asymptomatic Malawians is associated with children's growth failure

Evaluation of the BD MAX Enteric Parasite Panel for the detection of Cryptosporidium parvum/hominis, Giardia duodenalis and Entamoeba histolytica

Overview of Zoonotic Diseases in Turkey: The One Health Concept and Future Threats

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