Gill and head kidney antioxidant processes and innate immune system responses of yellow perch (Perca flavescens) exposed to different contaminants in the St. Lawrence River, Canada

Dautremepuits, Claire; Marcogliese, David J.; Gendron, Andrée D.; Fournier, Michel

doi:10.1016/j.scitotenv.2008.10.004

Cited by 77 publications

(34 citation statements)

References 61 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…BEA has high concentrations of PCBs, organochlorines, and heavy metals including copper, arsenic, lead, chromium, nickel, and zinc. Mercury levels are particularly high and surpass the PEL Dautremepuits et al 2009). …”

Section: Study Localitiesmentioning

confidence: 99%

“…The pollution status of all five localities has been previously characterized based on sediment measurements of metals and polychlorinated biphenyls (PCBs) (Loiselle et al 1997;Marcogliese et al 2005Marcogliese et al , 2006Dautremepuits et al 2009). Sediment measurements are appropriate because they are relatively stable over time (Dautremepuits et al 2009). They are also of particular biological importance for our study system because johnny darters are benthic fish and therefore are in close contact with them.…”

Section: Study Localitiesmentioning

confidence: 99%

“…In natural environments, pollutants typically occur as combinations of chemicals. These complex mixtures can produce unpredictable or nonlinear affects on aquatic life (Pietrock and Marcogliese 2003;Dautremepuits et al 2009). Their toxicity may be further affected by other abiotic factors such as pH and temperature (Poulin 1992;Lafferty 1997;Pietrock and Marcogliese 2003;Marcogliese 2005).…”

Section: Introductionmentioning

confidence: 99%

“…Various locations are exposed to differing amounts of these contaminants. Within this system, effects of pollution have been examined on immune response, stress response, and parasitism in spottail shiners (Notropis hudsonius) and yellow perch (Perca flavescens) Marcogliese et al 2005Marcogliese et al , 2006Thilakaratne et al 2007;Dautremepuits et al 2009); however, no effects of pollution have been measured for a benthic fish in this river. Effects of pollutants on benthic fish may be of particular interest because of the close proximity of these fish to the sediments; similar studies have been conducted on flatfish in marine environments (e.g.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Parasite fauna of Etheostoma nigrum (Percidae: Etheostomatinae) in localities of varying pollution stress in the St. Lawrence River, Quebec, Canada

2010

View full text Add to dashboard Cite

Parasite communities were examined in johnny darters (Etheostoma nigrum) collected from five localities in the St. Lawrence River in southwestern Quebec: two reference localities, one polluted locality upstream of the Island of Montreal and downstream of industrial and agricultural activity, and two polluted localities downstream of the Island of Montreal in the plume from the wastewater treatment facility. Twenty-four helminth species were found. Fish from the upstream polluted locality had the highest parasite species richness and total parasite numbers, and fish from the downstream polluted localities the lowest. Nonmetric multivariate analyses were conducted using square-root-transformed Bray-Curtis dissimilarity index. An analysis of similarity, dendrogram of centroids, and a permutational multivariate analysis of variance with contrasts all showed that fish from the reference localities had different parasite community composition than those from the polluted localities, and fish from the upstream polluted locality had different parasite communities than fish from the downstream polluted localities. Differences between reference and polluted localities were mainly due to higher abundances of the brain-encysting trematode, Ornithodiplostomum sp., at the reference localities. Differences between upstream and downstream polluted localities were mainly due to a higher diversity and abundance of trematodes in fish at the upstream locality.

show abstract

Section: Study Localitiesmentioning

confidence: 99%

Section: Study Localitiesmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Parasite fauna of Etheostoma nigrum (Percidae: Etheostomatinae) in localities of varying pollution stress in the St. Lawrence River, Quebec, Canada

2010

View full text Add to dashboard Cite

show abstract

“…For example, increasing the activities of cytosolic CuZnSOD and CAT via transgenic overexpression increases cell viability by up to 33% in Drosophila melanogaster (Orr and Sohal 1994;Schriner et al 2005). GRd activity in both gill and head kidney tissue of fish was reported to increase with increasing site contamination (Dautremepuits et al 2009). Hence, antioxidant enzymes are thought to provide enhanced resistance to oxidative stress.…”

Section: Stress Biomarkers Of Aquatic Contaminationmentioning

confidence: 99%

Physiological Adaptations of Stressed Fish to Polluted Environments: Role of Heat Shock Proteins

Perumal

2010

Reviews of Environmental Contamination and Toxicology

View full text Add to dashboard Cite

Fish are subjected to a wide variety of environmental stressors. Stressors affect fish at all life stages and the stress-specific responses that occur at the biochemical and physiological levels affect the overall health and longevity of such animals. In this review, the organ-specific alterations in fish that inhabit polluted environments are addressed in detail. Fish,like other vertebrates, have evolved strategies to counteract stress-mediated effects. Among the key strategies that fish have developed is the induction of HSPs. The primary functions of HSPs are to promote the proper folding or refolding of proteins, to prevent potentially damaging interactions with proteins, and aiding in the disassembly of formations of protein aggregates. Stress, a state of unbalanced tissue oxidation, causes a general disturbance in the cellular antioxidant and redox balance and evokes HSP70 overexpression. Distinct families of HSPs have diverse physiological functions, and their induction, which is regulated at the transcriptional level, is mediated by the activation of heat shock factors. Interestingly, HSPs also interact with a wide variety of signaling molecules that modulate stress-mediated apoptotic effects. Hence, HSP induction is of major importance for maintenance of cell homeostasis. HSP-mediated adaptation processes are regarded as a fundamental protective mechanism that decreases cellular sensitivity to damaging events. Thus, the adaptive expression of HSPs is a protective response that helps combat stress-induced conformational damage to proteins. Additional research is needed to gain further information on the functional significance and role of individual HSPs and to enhance the understanding of the molecular mechanisms by which they act. In addition, field studies are needed to allow comprehensive evaluation of the potential use of HSPs as biomarkers for environmental monitoring. Furthermore, the expression of HSPs in fish fluctuates in response to seasonal variation. Because HSPs serves as a tool for assessing the stressed state of individuals and/or populations, the impact of seasonal influences on constitutive and inducible factors of these proteins should also be elucidated. Such research will lead to a fundamental improvement in the understanding of the functional role of HSPs in response to natural environmental changes and may allow correlation of the action of HSPs at the molecular level with the whole organismal stress response, which, so far, remains unexplained.

show abstract

A comparative study on the effects of three different metals (Cu, Zn and Cd) at similar toxicity levels in common carp, Cyprinus carpio

Castaldo

Delahaut

Slootmaekers

et al. 2020

J of Applied Toxicology

View full text Add to dashboard Cite

To improve our understanding of underlying toxic mechanisms, it is important to evaluate differences in effects that a variety of metals exert at concentrations representing the same toxic level to the organism. Therefore, the main goal of the present study was to compare the effects of waterborne copper (Cu(II)), zinc (Zn(II)) and cadmium (Cd (II)) on a freshwater fish, the common carp (Cyprinus carpio), at concentrations being 0%, 25%, 50% and 100% of the 96 h LC50 (the concentration which is lethal to 50% of the population in 96 h). All the exposures were performed for a period of 1 week at 20°C. Our results show a rapid increase in the amount of copper and cadmium accumulated in the gills, while zinc only started to increase by the end of the experiment. All three metal ions increased metallothionein gene expression in both gills and liver. However, clear adverse effects were mainly observed for the Cu exposed group. Cu caused a decrease in Na level in gill tissue; it altered the expression of genes involved in ionoregulation such as Na+/K+‐ATPase and H+‐ATPase as well as the expression of oxidative stress‐related genes, such as catalase, glutathione reductase and glutathione S‐transferase. Zinc and cadmium exposure did not alter the ion levels in the gills. In addition, no obvious effect of oxidative stress was observed, except for a transient increase in glutathione reductase at the highest cadmium concentration.

show abstract

Gill and head kidney antioxidant processes and innate immune system responses of yellow perch (Perca flavescens) exposed to different contaminants in the St. Lawrence River, Canada

Cited by 77 publications

References 61 publications

Parasite fauna of Etheostoma nigrum (Percidae: Etheostomatinae) in localities of varying pollution stress in the St. Lawrence River, Quebec, Canada

Parasite fauna of Etheostoma nigrum (Percidae: Etheostomatinae) in localities of varying pollution stress in the St. Lawrence River, Quebec, Canada

Physiological Adaptations of Stressed Fish to Polluted Environments: Role of Heat Shock Proteins

A comparative study on the effects of three different metals (Cu, Zn and Cd) at similar toxicity levels in common carp, Cyprinus carpio

Contact Info

Product

Resources

About