Ginger honey affects cortisol, estrogen and glutathione levels; preliminary study to target preconceptional women

Usman, Andi Nilawati; Raya, Indah; Yasmin, Riska; Aliyah,; Dirpan, Andi; Arsyad, Aryadi; Permatasari, Annisa; Sumidarti, Andi; Umami, Nurrahmi; Emmasitah,

doi:10.1016/j.gaceta.2021.07.018

Cited by 7 publications

(4 citation statements)

References 23 publications

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“…Ginger appears to enhance long-term implantation in rats at shorter doses and could have potential as a natural alternative or adjunct with minimal side effects in boosting fertility [46]. This is further supported in a study by Usman et al [47] where ginger honey supplementation in stress-induced mice increased estrogen and glutathione levels significantly, while not affecting cortisol levels in comparison to standard feed alone. However, the coadministration of honey in this study serves as a confounding variable.…”

Section: Ginger (Zingiber Officinale)mentioning

confidence: 65%

Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health

Patibandla,

Gallagher,

Patibandla

et al. 2024

Cureus

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Ayurveda, an ancient holistic and personalized healing system originating from the Indian subcontinent, has been gaining increasing attention as a complementary and alternative medical practice for treating various health conditions, including those related to women's reproductive well-being. This comprehensive literature review examines a wide array of experimental and clinical studies exploring the diverse facets of Ayurvedic interventions in addressing issues such as menstrual irregularities, polycystic ovary syndrome (PCOS), infertility, and menopausal symptoms. The paper specifically focuses on discussing the available data regarding the efficacy of Tulsi (Ocimum tenuiflorum), ashwagandha (Withania somnifera), ginger (Zingiber officinale), cardamom (Elettaria cardamomum), turmeric (Curcuma longa), and Shatavari (Asparagus racemosus), which have traditionally been used in Ayurvedic medicine for centuries. The synthesis of literature not only highlights the potential benefits of these Ayurvedic interventions, but also critically assesses the methodological rigor of existing studies, identifying research gaps, and proposing directions for future investigations. While acknowledging the need for further rigorous research and clinical trials, the review emphasizes the benefits of collaborative and integrative healthcare. This review aims to serve as a valuable resource for healthcare practitioners, researchers, and individuals seeking holistic and natural alternatives for female reproductive health management.

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Section: Ginger (Zingiber Officinale)mentioning

confidence: 65%

Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health

Patibandla,

Gallagher,

Patibandla

et al. 2024

Cureus

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“…These results is confirmed by prior studies will be suggest that ginger extractor contains inactive ingredient antioxidants that have effect on the regulation of gonadotropin production like gingerols and shogaols which block production of arachidonic acids by interpose with lipooxygenase, pathways cyclooxygenase and that way lead to prevent production of prostaglandin (Hosseini & Jahandideh 2015, Solmaz, 2020, Harrison, et al 2011. Furthermore, survey about ginger extract had shown that it have anti androgenic effects such as, polyphenolic compounds and flavonoids with their specify physiological and pharmacological effects could rebalanced any disorders in sex hormones (Montazeri, et al 2018, Andi, et al 2021. Moreover, ginger have the ability to increase glutathione level which act as anti-oxidant and hydrogen donors to free radicals to prevent oxidative stress which is a trigger for oocyte damage and infertility as well as lead to increase estrogen hormone levels (Amanda, et al 2017, Loucks, andThuma, 2003).…”

Section: Resultsmentioning

confidence: 99%

The Effectiveness of Aqueous Extract of Ginger on Some Sex Hormones and Biochemical Parameters in Female Laboratory Mice (Mus Musculus L.)

Abd Almajeed,

Ibrahim

2024

VMPH

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Objective: Ginger is a flowering tropical plant that commonly used as a spice and flavoring having various pharmacological properties, several phytochemical compounds which has biological activity. The main bioactive compound in ginger is gingerol, have a powerful anti-inflammatory effect will greatly affect on fertility. Also, it has an effective role in many laboratory experiments to study the physiological activities of ginger extract on these functions. Aim: This study aimed to investigate the effects of ginger extract on some sex hormones like estrogen, progesterone, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in female mice, also its effect on total protein, albumin and globulin Methods: Thirty adult female mice of (Mus Musculus L.) weight (22-24g) were derived into three groups one control and two treated. Ginger water extract be ready to prepare with affecting doses according to experimental test on mice (3.5 and 7 mg body weight/mice). The concentration of serum female sex hormones (FSH, LH, progesterone and estrogen) were measured. Results: Ginger water extract caused a significant increase in the level of estrogen in both doses and significant increase in the level of FSH and LH in high dose only (P less than 0.01). While progesterone level show no significant changes. On the other hand, the serum total protein, albumin and globulin shows a significant increase only in total protein and globulin levels (P less than 0.01) in turn albumin level show no significant changes in comparison to control. Conclusion: The results of this study, ginger extract could increase the level of female sex hormones (estrogen, FSH and LH) and conceder as adjunctive natural therapy for improvement of female sex hormones as well as lead to increase in total protein and globulin level which is essential for boosting the immunity.

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“…Overcoming migraines [37] Ginger honey was shown to reduce cortisol hormone levels in experimental animals given ginger honey as much as 42 mg / 20g body weight.…”

Section: Referencementioning

confidence: 99%

Analysis of Ginger Varieties (Zingiber Officinale) in Indonesia, Nutritional Content and Potential for Health

Fitri Yanti,

Nilawati Usman,

Ahmad

et al. 2024

BIO Web Conf.

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Ginger (Zingiber officinale) is a traditional spice that is widely used as a medicine with a myriad of benefits because it is rich in nutrients and bioactive compounds that are used in health. Examining the character of various varieties of ginger in Indonesia, nutritional content, pharmacology, and their potential for health. Literature study by reviewing 30 references to publication articles in national and international journals accessed through sciencedirect, google scholar, Pubmed, wiLey. In Indonesia there are 3 varieties of ginger, namely sunti ginger, gajah ginger and emprit ginger. Nutritional content including, energy, carbohydrates, fiber, protein, sodium, iron, potassium and vitamins. Pharmacological activities in ginger include antioxidants, anti-inflammatory, analgesic, antibacterial and antiviral Ginger for health can be used to overcome nausea, vomiting, coughing, relieving headaches, and dealing with stress. Ginger contains many nutrients and is beneficial for health.

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Ginger honey affects cortisol, estrogen and glutathione levels; preliminary study to target preconceptional women

Cited by 7 publications

References 23 publications

Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health

Ayurvedic Herbal Medicines: A Literature Review of Their Applications in Female Reproductive Health

The Effectiveness of Aqueous Extract of Ginger on Some Sex Hormones and Biochemical Parameters in Female Laboratory Mice (Mus Musculus L.)

Analysis of Ginger Varieties (Zingiber Officinale) in Indonesia, Nutritional Content and Potential for Health

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