Gingival crevicular fluid levels of protease‐activated receptors type 1 and type 2 in diabetic patients with periodontitis

Abstract

The present data demonstrated that diabetes was associated with an altered expression of PAR1 and PAR2 in the gingival crevicular fluid cells of subjects with chronic periodontitis. Future studies are necessary to elucidate the effects of PAR1 upregulation in periodontally healthy sites and PAR2 downregulation in chronic periodontitis sites on the increased susceptibility and severity of periodontitis in diabetes.

Oral health‐related quality of life and periodontal status according to smoking status

“…Despite the lack of statistical significance, there was a trend toward greater total mean (±standard deviation) of OHIP‐14 scores for current smokers patients (15 ± 14) compared with never (10 ± 8) and former smokers (13 ± 11). These results were within the previously reported values that found no significant difference in OHIP‐14 scores related to smoking 15,23–25 . Shay et al 23 compared 63 patients with nutritional disorders to 100 control patients to assess OHIP‐14 scores and found no significant correlation with smoking pack‐years ( R = 0.019; p = 0.842).…”

“…These results were within the previously reported values that found no significant difference in OHIP-14 scores related to smoking. 15,[23][24][25] Shay et al 23 compared 63 patients with nutritional disorders to 100 control patients to assess OHIP-14 scores and found no significant correlation with smoking pack-years (R = 0.019; p = 0.842). Masood et al 25 evaluated a subset of elderly (≥65 year) participants from the UK Adult Dental Health Survey 2009 data.…”