Gingival enlargement in myelodysplastic syndrome

George, Navia; Santhosh, Vediyera Chandroth; Kumar, Harish; Gopal, Saumiya

doi:10.4103/0972-124x.164761

Cited by 4 publications

(10 citation statements)

References 8 publications

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“…Oral manifestations of leukemia include petechiae or spontaneous bleeding in 56% of patients [1,2,5,22], mucosal ulceration in 53% [1][2][3][4][5], and gingival enlargement in 36% [1,6,11,22,23], with or without necrosis [5]. These features are the most common initial diagnostic manifestations of leukemia.…”

Section: Oral Manifestationsmentioning

confidence: 99%

“…Gingival enlargement and ulcerations may be due to either neutropenia or direct infiltration of immature (blasts) proliferating leukocytes, or be secondary to thrombocytopenia and immunodeficiency [1,5,23]. This infiltration leads to an increase in gingival thickness and formation of pseudo-pockets, resulting in secondary inflammatory infiltration [1].…”

Section: Gingival Alterationsmentioning

confidence: 99%

“…Despite being rarely reported in the literature [1], gingival enlargement may be the first manifestation of acute leukemia, especially in AML [1,8,11,23]. The overgrowth of gingiva is characterized by an accumulation of connective tissue with the presence of an increased number of cells.…”

Section: Gingival Alterationsmentioning

confidence: 99%

“…The overgrowth of gingiva is characterized by an accumulation of connective tissue with the presence of an increased number of cells. According to the etiologic factors and pathologic changes, gingival enlargement can be classified as inflammatory, drug-induced, neoplastic, false enlargement, and is often associated with systemic diseases (in particular, granulomatous diseases and leukemia) [1,23].…”

Section: Gingival Alterationsmentioning

confidence: 99%

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Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia

Cammarata‐Scalisi

Girardi

Strocchio

et al. 2020

Cancers

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Acute myeloid leukemia (AML) is a heterogeneous group of diseases, whose classification is based on lineage-commitment and genetics. Although rare in childhood, it is the most common type of acute leukemia in adults, accounting for 80% of all cases in this age group. The prognosis of this disease remains poor (especially in childhood, as compared to acute lymphoblastic leukemia); however, overall survival has significantly improved over the past 30 years. The health of the oral cavity is a remarkable reflection of the systemic status of an individual. Identification of the signs and symptoms of oral lesions can act as a warning sign of hidden and serious systemic involvement. Moreover, they may be the presenting feature of acute leukemia and provide important diagnostic indicators. Primary oral alterations are identified in up to 90% of cases of acute myeloid leukemia and consist of petechiae, spontaneous bleeding, mucosal ulceration, gingival enlargement with or without necrosis, infections, hemorrhagic bullae on the tongue, and cracked lips. Poor oral hygiene is a well-known risk factor for local and systemic infectious complications. Oro-dental complications due to AML treatment can affect the teeth, oral mucosa, soft and bone tissue, and contribute to opportunistic infections, dental decay, and enamel discoloration. The treatment of acute myeloid leukemia is still associated with high mortality and morbidity. The management is multimodal, involving aggressive multidrug chemotherapy and, in most cases, allogenic bone marrow transplantation. Periodontal and dental treatment for patients with leukemia should always be planned and concerted with hematologists.

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Section: Oral Manifestationsmentioning

confidence: 99%

Section: Gingival Alterationsmentioning

confidence: 99%

Section: Gingival Alterationsmentioning

confidence: 99%

Section: Gingival Alterationsmentioning

confidence: 99%

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Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia

Cammarata‐Scalisi

Girardi

Strocchio

et al. 2020

Cancers

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“…The presence of an increased number of cells and a buildup of connective tissue characterizes gingiva overgrowth [ 24 ]. As previously stated, gingival infiltration is more common in myelomonocytic and monocytic leukemia, and the proposed hypothesis for gingival involvement is based on the microanatomy of the gingiva and the expression of endothelial adhesion molecules, which allows leukocyte infiltration and leads to a soft overgrowth [ 24 , 28 , 29 ]. As a result of the infiltration, gingival thickness increases, and pseudo-pockets develop, leading to subsequent inflammatory infiltration [ 27 , 28 ].…”

Section: Reviewmentioning

confidence: 99%

Epidemiological Trends and Clinical Characteristics of Childhood Leukemia in Saudi Arabia: A Review

Owaidhah¹,

Khawaji²,

Alahmadi³

et al. 2022

Cureus

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Leukemia is the most prevalent type of cancer among children in Saudi Arabia. It has variable clinical presentations and accounts for a large scale of mortality and morbidity. Acute lymphoblastic leukemia (ALL) constituted the majority of pediatric leukemic cases with male gender predisposition. The most common first presentation that patients come with are manifestations of anemia, thrombocytopenia, and fever. Bone pain, fatigue, weight loss, organomegaly, and pale skin are among the commonest manifestations of pediatric leukemia. Childhood ALL and acute myeloid leukemia (AML) clinical manifestations seem to be very similar, even though there're some considerable differences in how common the clinical characteristics are. Chromosomal abnormalities are taken into consideration to determine survival and treatment. PubMed and Google Scholar were searched for the childhood leukemia population in Saudi Arabia. Our review article aims at providing comprehensible and updated statistical data on the different types of leukemia and their clinical presentations in Saudi Arabia.

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Advances in Superhydrophobic Coatings

2023

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Superhydrophobic coatings have attracted substantial scientific research in recent years due to their real-world applications in a variety of fields including anti-corrosion, anti-icing, anti-fogging, oil separation and self-cleaning materials. Several approaches and methods have been used in developing superhydrophobic coatings on different substrates. This book guides readers through their fabrication and application, representing the latest significant advances in this important topic. Split into four sections, Part One concentrates on the fundamental principles of surface wettability and superhydrophobicity, before moving into Part Two and Part Three, which focus on different aspects of superhydrophobic coatings based on the materials used for fabrication and the substrate on which the coating is applied. Finally, Part Four focuses on the applications of these coatings. This book will serve as a valuable reference for graduate students, researchers and industrial practitioners in multiple industries working on surface wettability, materials chemistry and coatings related technologies.

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Gingival enlargement in myelodysplastic syndrome

Cited by 4 publications

References 8 publications

Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia

Oral Manifestations and Complications in Childhood Acute Myeloid Leukemia

Epidemiological Trends and Clinical Characteristics of Childhood Leukemia in Saudi Arabia: A Review

Advances in Superhydrophobic Coatings

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