Glass-ceramics in dentistry: Fundamentals, technologies, experimental techniques, applications, and open issues

Montazerian, Maziar; Baino, Francesco; Fiume, Elisa; Migneco, Carla; Alaghmandfard, Amirhossein; Sedighi, Omid; DeCeanne, Anthony V.; Wilkinson, Collin J.; Mauro, John C.

doi:10.1016/j.pmatsci.2022.101023

Cited by 42 publications

(26 citation statements)

References 443 publications

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“…Dental glass-ceramics of this kind are developed by the controlled crystallization of oxide glasses and form an important group of biomaterials used in modern dentistry. They are designed to have exceptional aesthetics, translucency, high strength, chemical durability, wear resistance, biocompatibility, low thermal conductivity, hardness, and radiopacity [ 138 ]. Höland et al [ 137 ] precipitated Sr-doped fluoroapatite in SiO 2 –Al 2 O 3 –Y 2 O 3 –SrO–Na 2 O–K 2 O/Rb 2 O/Cs 2 O–P 2 O 5 –F base glass compositions.…”

Section: Radiopacifiers In Glasses and Glass-ceramicsmentioning

confidence: 99%

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

et al. 2022

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Radiopacity is sometimes an essential characteristic of biomaterials that can help clinicians perform follow-ups during pre- and post-interventional radiological imaging. Due to their chemical composition and structure, most bioceramics are inherently radiopaque but can still be doped/mixed with radiopacifiers to increase their visualization during or after medical procedures. The radiopacifiers are frequently heavy elements of the periodic table, such as Bi, Zr, Sr, Ba, Ta, Zn, Y, etc., or their relevant compounds that can confer enhanced radiopacity. Radiopaque bioceramics are also intriguing additives for biopolymers and hybrids, which are extensively researched and developed nowadays for various biomedical setups. The present work aims to provide an overview of radiopaque bioceramics, specifically crystalline, non-crystalline (glassy), and nanostructured bioceramics designed for applications in orthopedics, dentistry, and cancer therapy. Furthermore, the modification of the chemical, physical, and biological properties of parent ceramics/biopolymers due to the addition of radiopacifiers is critically discussed. We also point out future research lacunas in this exciting field that bioceramists can explore further.

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Section: Radiopacifiers In Glasses and Glass-ceramicsmentioning

confidence: 99%

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

et al. 2022

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Section: Bioactive Glasses (Bgs)mentioning

confidence: 99%

Gelatin and Bioactive Glass Composites for Tissue Engineering: A Review

Barreto

Medeiros

Shearer

et al. 2022

JFB

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Nano-/micron-sized bioactive glass (BG) particles are attractive candidates for both soft and hard tissue engineering. They can chemically bond to the host tissues, enhance new tissue formation, activate cell proliferation, stimulate the genetic expression of proteins, and trigger unique anti-bacterial, anti-inflammatory, and anti-cancer functionalities. Recently, composites based on biopolymers and BG particles have been developed with various state-of-the-art techniques for tissue engineering. Gelatin, a semi-synthetic biopolymer, has attracted the attention of researchers because it is derived from the most abundant protein in the body, viz., collagen. It is a polymer that can be dissolved in water and processed to acquire different configurations, such as hydrogels, fibers, films, and scaffolds. Searching “bioactive glass gelatin” in the tile on Scopus renders 80 highly relevant articles published in the last ~10 years, which signifies the importance of such composites. First, this review addresses the basic concepts of soft and hard tissue engineering, including the healing mechanisms and limitations ahead. Then, current knowledge on gelatin/BG composites including composition, processing and properties is summarized and discussed both for soft and hard tissue applications. This review explores physical, chemical and mechanical features and ion-release effects of such composites concerning osteogenic and angiogenic responses in vivo and in vitro. Additionally, recent developments of BG/gelatin composites using 3D/4D printing for tissue engineering are presented. Finally, the perspectives and current challenges in developing desirable composites for the regeneration of different tissues are outlined.

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“…The action of different ions that stimulate cellular metabolism allows the application of these materials in the repair of bone defects, tissue regeneration, wound healing, cell support, drug delivery, etc. [1,93,127,128] Studies published in recent years have proven that these materials can act with similar efficacy to classic orthopedic applications in the treatment of difficult-to-heal wounds and in the control of hemorrhages through the release of SiO4 -4 species. These units stimulate the signaling of growth factors and proteins in addition to promoting the activation of clotting factors, processes that are essential for accelerating the proliferation of epithelial cells and reducing inflammation.…”

Section: Bioactive Glasses (Bgs)mentioning

confidence: 99%

Gelatin and Bioactive Glass Composites for Tissue Engineering: A Review

Barreto¹,

Medeiros²,

Shearer³

et al. 2022

Preprint

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Nano/micron-sized bioactive glass (BG) particles are attractive candidates for both soft and hard tissue engineering. They can chemically bond to the host tissues, enhance new tissue formation, activate cell proliferation, stimulate the genetic expression of proteins, and trigger unique an-ti-bacterial, anti-inflammatory, and anti-cancer functionalities. Recently, composites based on bi-opolymers and BG particles have been developed with various state-of-the-art techniques for tis-sue engineering. Gelatin, a semi-synthetic biopolymer, has attracted the attention of researchers because it is derived from the most abundant protein in the body, viz., collagen. It is a polymer that can be dissolved in water and processed to acquire different configurations, such as hydro-gels, fibers, films, scaffolds, etc. Searching "bioactive glass gelatin" in the tile on Scopus renders 80 highly relevant articles published in the last ~10 years, which signifies the importance of such composites. First, this review addresses the basic concepts of soft and hard tissue engineering, in-cluding the healing mechanisms and limitations ahead. Then, current knowledge on gelatin/BG composites including composition, processing and properties is summarized and discussed both for soft and hard tissue applications. This review explores physical, chemical and mechanical features and ion-release effects of such composites concerning osteogenic and angiogenic respons-es in vivo and in vitro. Additionally, recent developments of BG/gelatin composites using 3D/4D printing for tissue engineering are presented. Finally, the perspectives and current challenges in developing desirable composites for the regeneration of different tissues are outlined.

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Glass-ceramics in dentistry: Fundamentals, technologies, experimental techniques, applications, and open issues

Cited by 42 publications

References 443 publications

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

Radiopaque Crystalline, Non-Crystalline and Nanostructured Bioceramics

Gelatin and Bioactive Glass Composites for Tissue Engineering: A Review

Gelatin and Bioactive Glass Composites for Tissue Engineering: A Review

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