Glassy Carbon Electrode Modified via Molybdenum Disulfide Decorated Multiwalled Carbon Nanotubes for Sensitive Voltammetric Detection of Aristolochic Acids

Abstract

In this study, a molybdenum disulfide/multiwalled carbon nanotubes (MoS2@MWCNTs) nanocomposite was synthesized by employing a simple hydrothermal method. The flower‐like structure of the MoS2@MWCNTs was characterized via scanning electron microscopy (SEM) and transmission electron microscopy (TEM), and the load of crystalline MoS2 was verified via X‐ray diffraction (XRD) and energy‐dispersive spectroscopy (EDS). The as‐prepared MoS2@MWCNTs nanocomposite was used to modify glassy carbon electrode (GCE) as an electrochemical sensor for detecting aristolochic acids (AAs). With the optimized parameters, the proposed electrochemical sensor exhibited good sensitivity and a broad linear concentration range for detecting AAs from 0.2 to 10 μmol/L and 10 to 100 μmol/L, with the sensitivity of −3.10 μA/(μmol/L) and −0.91 μA/(μmol/L), respectively. The detection limit was also calculated as 0.06 μmol/L (S/N=3) based on the low background signal. Furthermore, the modified electrochemical sensor exhibited good selectivity, repeatability, reproducibility, and stability, thus showing potential application for detecting AA in chinese herbs with good mean recovery and accuracy. In other words, the MoS2@MWCNTs/GCE can be used as an excellent platform to detect AAs.

Detection and Removal of Aristolochic Acid in Natural Plants, Pharmaceuticals, and Environmental and Biological Samples: A Review

“…Wang et al prepared cyclic voltammetry sensors by modifying glassy carbon electrode materials to improve the sensitivity of detection. MoS 2 @MWCNTs nanocomposites [ 73 ] and ordered mesoporous carbon materials [ 74 ] were used to detect AAs via cyclic voltammetry and linear sweep voltammetry. Although the sensor has a low detection limit, a high test range, and relatively low cost, it exhibits poor stability during detection and is easily affected by pH and temperature.…”

A Novel Molecularly Imprinted Electrochemical Sensor Based on PANI@GO for Highly Sensitive and Selective Analysis of Trace Epigoitrin

“…10,11 Y. Wang et al construct an electrochemical sensor base on multiwalled carbon nanotubes to detect aristolochic acids, which showed excellent analyzing performance. 12 C. Damphathik et al have developed an electrochemical sensor for determination of artemisinin, which had been applied to drug and plant samples. 13 In addition, with development of the electrochemical sensing system and Internet of things (IoT) in recent years, it has been paid more and more attention to the quality transitivity and traceability system of herbal medicine products based on indicator compounds, which also provides a high-speed way for the highquality development of traditional Chinese medicines and herbs.…”