Glaucoma in Fuchs' heterochromic uveitis: Aetiology, management and outcome

Jones, Nicholas P.

doi:10.1038/eye.1991.122

Cited by 70 publications

(42 citation statements)

References 21 publications

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“…This is particularly troubling since this disease occurs in children with chronic inflammation that has so often been present before and after involvement of an ophthalmologist [21]. Such chronic or recurrent inflammation may explain why 7 of 11 JRA-associated uveitis patients with glaucoma had uncontrolled glaucoma at the time of the data analysis.…”

Section: Discussionmentioning

confidence: 99%

Secondary Glaucoma in Patients with Uveitis

Merayo‐Lloves

Power²,

Rodriguez³

et al. 1999

Ophthalmologica

136

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Purpose: To evaluate the prevalence of secondary glaucoma (SG), clinical forms of uveitis more frequently associated with glaucoma, and describe the treatment and complications encountered in a cohort of patients with glaucoma and uveitis during a 10-year period. Methods: The hospital records of patients with uveitis referred to the Immunology Service of the Massachusetts Eye and Ear Infirmary for a decade were reviewed for cases of SG. Results: One hundred and twenty of the 1,254 patients (9.6%) with uveitis developed SG. SG was more frequent in anterior uveitis (67%) but was also associated with posterior uveitis (13%) and pars planitis (4%). Herpetic keratouveitis (22%), Fuchs’ iridocyclitis (19%), juvenile rheumatoid arthritis-associated iridocyclitis (16%), syphilis (14%), and sarcoidosis (12%) were the leading types of uveitis associated with SG. Despite aggressive medical and surgical therapy, SG was associated with progressive visual field loss and optic nerve damage in 39 patients (33%). Conclusion: SG is an underappreciated, vision-threatening complication in patients with uveitis. Increased vigilance for emergence of this complicating problem during the care of patients with uveitis is warranted, and medical and surgical treatment for reducing IOP should be especially aggressive in these patients. We hypothesize that earlier, more aggressive treatment of uveitis will reduce the presence of glaucoma as an additional vision-robbing complication of uveitis.

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Section: Discussionmentioning

confidence: 99%

Secondary Glaucoma in Patients with Uveitis

Merayo‐Lloves

Power²,

Rodriguez³

et al. 1999

Ophthalmologica

136

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“…O glaucoma secundário desses pacientes não é resultado de uma trabeculite responsiva aos esteróides, a drenagem do ângulo é normalmente aberta e apesar de poder ocorrer sinéquias anteriores perifé-ricas elas não são regulares (4)(5) .…”

Section: Discussionunclassified

“…O glaucoma está presente em 15 a 59% dos casos, mas o mecanismo de aumento da pressão intraocular é pobremente entendido (4)(5) . Recentes estudos sugerem que esta desordem usualmente é resistente à medicação e que apenas a cirurgia tem chance de moderado sucesso (4) .…”

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Glaucoma secundário à iridociclite heterocrômica de Fuchs

Cordeiro¹,

Barros²,

Rehder³

2011

Rev. bras.oftalmol.

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RESUMOA iridociclite heterocrômica de Fuchs ou Síndrome de Fuchs é um tipo de uveíte relativamente incomum. Afeta igualmente ambos os sexos, na faixa etária dos 20-45 anos, tendo no quadro clássico uma inflamação não granulomatosa crônica unilateral na úvea anterior, de início insidioso, baixo grau de atividade, e não sendo responsiva aos corticóides. Normalmente tem um bom prognóstico, exceto quando ocorre o desenvolvimento de catarata e glaucoma, patologias que podem estar associadas à síndrome. Nesse caso, temos um paciente masculino, de 68 anos, que teve como primeira manifestação da síndrome o glaucoma.

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“…10 A hyphema may also occur in association with trivial trauma, gonioscopy, applanation tonometry, or mydriasis spontaneously. 11,13,26 The occurrence of hyphema does not necessarily correlate with the clinical signs of iris neovascularization or with the presence of abnormal vessels in the iridocorneal angle. 10,11 Vitreous cells are present in almost all patients with FUS.…”

Section: Chapter 43mentioning

confidence: 94%

“…Others describe the heterochromia or iris changes since youth. 10,13,14 Daylight examination is usually best for detecting subtle heterochromia. A heterochromia is usually most evident in blue-eyed patients (Figs.…”

Section: History and Clinical Featuresmentioning

confidence: 99%