Glaucoma in Patients With Endothelial Keratoplasty

Saini, Chhavi; Davies, Emma C.; Chodosh, James; Shen, Lucy Q.

doi:10.1097/ico.0000000000003122

Cited by 4 publications

(2 citation statements)

References 127 publications

(302 reference statements)

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“…Patients were excluded if they were under 21 years of age, had corneal abnormalities that might render IOP measurements inaccurate (severe epithelial/stromal edema, large central scars), patients with corneal dystrophies, previous corneal refractive surgery or corneal transplantation, active ocular infection, poor cooperation, or refused to participate. Prior corneal refractive surgery as well as corneal transplants affects the overall reliability of IOP measurements (11)(12)(13). Furthermore, since corneal thickness was not measured, these patients were excluded.…”

Section: Patient Selectionmentioning

confidence: 99%

A comparison of intraocular pressure measurement using SUOER SW-500 rebound tonometer and conventional reusable Goldmann prisms

Chaung,

Sangapillai,

Quilat

et al. 2024

Front. Med.

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IntroductionTo determine the agreement between intraocular pressure (IOP) measurements using conventional Goldmann applanation tonometry (GA1,2T) and SUOER SW-500 Rebound Tonometer.MethodsThis was a retrospective observational study where 205 eyes of 106 glaucoma patients had their IOPs measured by 2 fellowship trained ophthalmologists. Data were analyzed using the Bland–Altman method of differences. Correlation was measured using the Pearson coefficient.ResultsMost of our patients were Chinese (88.7%) and female (51.9%). The average age was 66.9 years. The range of IOPs as measured by GAT was 2 to 58 mm Hg. Using the Bland–Altman method to compare GAT and SUOER SW-500 Rebound Tonometer. The tonometer overestimated the IOP by 0.5 mm Hg in the right eye and underestimated it by 0.1 mm Hg in the left eye. Overall, the tonometer overestimated the IOP by 0.2 mmHg. The Tonometer IOP correlated well with GAT, with a Pearson coefficient of correlation(r) of 0.89 (p < 0.001) for the right eye and 0.86 (p < 0.001) for the left eye, respectively. In patients with GAT IOP ≥ 21 mm Hg (n = 25), the Tonometer underestimated the IOP by 2.96 mm Hg.DiscussionThe IOP measurements from the SUOER SW-500 Rebound Tonometer correlates well with the conventional GAT in measuring the IOP within normal ranges of IOP. SUOER SW-500 Rebound Tonometer may be of use, especially if the risk of transmission of infection is high considering that the probes are disposable. It is easy to use and its small size and portability makes it useful in situations where the patient is unable to be examined at the slit lamp.

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Section: Patient Selectionmentioning

confidence: 99%

A comparison of intraocular pressure measurement using SUOER SW-500 rebound tonometer and conventional reusable Goldmann prisms

Chaung,

Sangapillai,

Quilat

et al. 2024

Front. Med.

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“…2 In a recent review of glaucoma in endothelial keratoplasty patients, the longest reported followup was 3 years. 3 The purpose of this study was to quantify longer-term risk of steroid-induced ocular hypertension/ glaucoma with long-term use of topical prednisolone acetate.…”

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confidence: 99%

Long-Term Risk of Steroid-Induced Ocular Hypertension/Glaucoma With Topical Prednisolone Acetate 1% After Descemet Stripping Endothelial Keratoplasty

Price

2023

Cornea

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The aim of this study was to assess the long-term risk of steroid-induced ocular hypertension and the need for glaucoma treatment with long-term use of topical prednisolone acetate 1% in patients without preexisting glaucoma. Methods:We retrospectively reviewed the charts of 211 patients without previous glaucoma, who underwent Descemet stripping endothelial keratoplasty (DSEK) and used topical prednisolone acetate long-term to prevent graft rejection. Dosing was 4 times daily for 4 months and tapered to once daily. The main outcomes were ocular hypertension (defined as intraocular pressure $24 mm Hg, or increase of $10 mm Hg over baseline) and initiation of glaucoma treatment. Results:The median patient age was 70 years (range: 34-94 years).The indications for DSEK were Fuchs dystrophy (88%), pseudophakic corneal edema (7%), failed DSEK (3%), and failed penetrating keratoplasty (2%). The median follow-up period was 7 years (range, 1-17 years). At 1, 5, and 10 years, the cumulative risks of steroid-induced ocular hypertension were 29%, 41%, and 49%, respectively, and the risks of requiring glaucoma treatment were 11%, 17%, and 25%, respectively. Among 35 eyes treated for glaucoma, 28 (80%) were managed medically and 7 (20%) had filtration surgery.Conclusions: Long-term use of potent topical corticosteroids, such as prednisolone acetate 1%, entails substantial risk of developing steroid-induced ocular hypertension, so frequent monitoring of intraocular pressure is required. With corneal transplantation, the risk can be mitigated by using techniques with a low inherent risk of rejection, such as Descemet membrane endothelial keratoplasty, whenever possible, to allow earlier reduction of steroid potency.

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Donor Corneal Endothelial Cell Maturity and Its Impact on Graft Survival in Glaucoma Patients Undergoing Corneal Transplantation

Kitazawa,

Toda,

Ueno

et al. 2024

American Journal of Ophthalmology

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Glaucoma in Patients With Endothelial Keratoplasty

Cited by 4 publications

References 127 publications

A comparison of intraocular pressure measurement using SUOER SW-500 rebound tonometer and conventional reusable Goldmann prisms

A comparison of intraocular pressure measurement using SUOER SW-500 rebound tonometer and conventional reusable Goldmann prisms

Long-Term Risk of Steroid-Induced Ocular Hypertension/Glaucoma With Topical Prednisolone Acetate 1% After Descemet Stripping Endothelial Keratoplasty

Donor Corneal Endothelial Cell Maturity and Its Impact on Graft Survival in Glaucoma Patients Undergoing Corneal Transplantation

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