Glaucoma secondary to congenital fibrovascular pupillary membrane: a single tertiary center experience

Successful removal of a congenital fibrovascular pupillary membrane in 2 cases with variable age at presentation and sparing of the crystalline lens

“…Histopathology evaluation revealed many types of cells in different case reports that suggested CFPM is a variant of persistent fetal vasculature [ [4] , [5] , [6] ]. Our first case was very similar in the histopathological constituents and appearance to that described by Kesarwani et.al with elongated spindle-shaped cells and adherent pigmented tissue [ 9 ]. The presence of more developed adherent iris tissue in the second case with a delayed presentation and longer history that indicated the absence of this membrane at birth, may support the theory of CFPM being related to the presence of an ectopic iris tissue at birth.…”

“…All cases had membranectomy, peripheral iridectomy, pupilloplasty, and goniosynechialysis as initial surgery. Following primary surgery, 4 patients had an intractably elevated IOP [ 9 ]. Additional surgeries including membranectomy, pupilloplasty, goniosynechialysis, cyclocryotherapy, ciliary photocoagulation, Ahmed valve implantation, and lensectomy were performed.…”

Use of ultrasound biomicroscopy to predict the outcome of anterior segment reconstruction in congenital fibrovascular pupillary membrane with secondary glaucoma

“…Liang et al published a small case series and nearly 50% of the 9 eyes with CFPMSG had uncontrolled IOP despite surgery. 10 Additionally, the risk factors related to the surgical outcome of CFPMSG remain unclear. In the current study, we found the classification system of UBM configurations we established for CFPMSG 13 is associated with Sporadic case reports, mainly as part of study in CFPM, have shown the effects of surgical treatment in CFPMSG, where PI and anterior chamber reconstruction were performed for an initial treatment as we did.…”

“…Liang et al published a small case series and nearly 50% of the 9 eyes with CFPMSG had uncontrolled IOP despite surgery. 10 Additionally, the risk factors related to the surgical outcome of CFPMSG remain unclear. In the current study, we found the classification system of UBM configurations we established for CFPMSG 13 is associated with the surgical outcome of ASR.…”

“…6 7 Several surgical approaches for removal of the membrane in CFPM have been reported; however, there is limited data on surgical treatment and prognosis for glaucoma secondary to CFPM. [8][9][10] Unlike CFPM, surgery for CFPMSG was more complicated due to the high IOP, corneal opacity, shallow anterior chamber depth (ACD) and tight adhesion of membrane and lens capsule. It is more challenging for intraoperative manipulation and postoperative stability.…”