Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone

Wang, Rui; Luo, Daoshu; Adam, MadehaIshag; Li, Gang; Makin, AmirMahmoud; Zhang, Xiaofen; Zhou, Lu-Xi; Liao, Xinyue; Zhao, Li

doi:10.4103/1673-5374.354517

Cited by 4 publications

(1 citation statement)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to forming myelin sheaths around axons and secreting neurotrophic factors, SCs can also regulate sensory perception and facilitate cell communications between synapses (Faroni et al, 2014). Moreover, it has been found that SCs also play a significant role in neuroinflammation and neuropathic pain (Wang et al, 2022;Adam et al, 2023;Chen et al, 2023).…”

Section: Schwann Cells and Peripheral Nerve Regeneration 21 Schwann C...mentioning

confidence: 99%

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

Ling,

He,

Zhang

et al. 2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

Peripheral nerve injury (PNI) is a neurological disorder caused by trauma that is frequently induced by accidents, war, and surgical complications, which is of global significance. The severity of the injury determines the potential for lifelong disability in patients. Artificial nerve scaffolds have been investigated as a powerful tool for promoting optimal regeneration of nerve defects. Over the past few decades, bionic scaffolds have been successfully developed to provide guidance and biological cues to facilitate Schwann cell myelination and orientated axonal growth. Numerous assessment techniques have been employed to investigate the therapeutic efficacy of nerve scaffolds in promoting the growth of Schwann cells and axons upon the bioactivities of distinct scaffolds, which have encouraged a greater understanding of the biological mechanisms involved in peripheral nerve development and regeneration. However, it is still difficult to compare the results from different labs due to the diversity of protocols and the availability of innovative technologies when evaluating the effectiveness of novel artificial scaffolds. Meanwhile, due to the complicated process of peripheral nerve regeneration, several evaluation methods are usually combined in studies on peripheral nerve repair. Herein, we have provided an overview of the evaluation methods used to study the outcomes of scaffold-based therapies for PNI in experimental animal models and especially focus on Schwann cell functions and axonal growth within the regenerated nerve.

show abstract

Section: Schwann Cells and Peripheral Nerve Regeneration 21 Schwann C...mentioning

confidence: 99%

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

Ling,

He,

Zhang

et al. 2023

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

Microstructural Alteration of Trigeminal Nerve in Patients with Classic Trigeminal Neuralgia Shown by Diffusion Tensor Imaging and Its Correlation with Vascular Compression and Pain

Guo

Shi

et al. 2023

World Neurosurgery

View full text Add to dashboard Cite

Effects of maternal nonylphenol exposure on the proliferation of glial cells in the brain of male offspring mice

Lee,

Shin,

et al. 2024

Animal Cells and Systems

View full text Add to dashboard Cite

Glial cell line-derived neurotrophic factor and brain-derived neurotrophic factor regulate the interaction between astrocytes and Schwann cells at the trigeminal root entry zone

Cited by 4 publications

References 52 publications

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

Progress in methods for evaluating Schwann cell myelination and axonal growth in peripheral nerve regeneration via scaffolds

Microstructural Alteration of Trigeminal Nerve in Patients with Classic Trigeminal Neuralgia Shown by Diffusion Tensor Imaging and Its Correlation with Vascular Compression and Pain

Effects of maternal nonylphenol exposure on the proliferation of glial cells in the brain of male offspring mice

Contact Info

Product

Resources

About