Glial choristoma of the tongue. Clinicopathological analysis of a case and pathogenetic insights

Corsi, Alessandro; Veccia, Norman; Riminucci, Mara

doi:10.5114/pjp.2017.69693

Cited by 5 publications

(10 citation statements)

References 42 publications

(106 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Two major theories regarding the pathogenesis of glial choristoma have been described. The first suggests that nasal and palatopharyngeal glial choristomas develop as a result of herniation of neural glial tissue from the developing brain due to failed embryonic development of the bony cranium 3 5 6 10. The presence of a fibrous stalk connecting some nasal choristomas with intracranial contents supports this theory 6.…”

Section: Discussionmentioning

confidence: 99%

“…Glial choristomas are rare congenital malformations found primarily in neonates and young children. Approximately 250 cases affecting the nasal area and 33 cases affecting the oral cavity have been described in the literature 3 4. No previous cases have been described in the Eastern Cape, South Africa.…”

Section: Discussionmentioning

confidence: 99%

“…No previous cases have been described in the Eastern Cape, South Africa. Within the oral cavity, the tongue is most commonly involved, followed by the palatopharyngeal complex 3–7 11 12. Few cases have been described which involve the infratemporal fossa.…”

Section: Discussionmentioning

confidence: 99%

“…Congenital masses of the deep neck spaces and oral cavity are rare and usually benign in nature but may potentially cause life threatening upper airway obstruction 1 2. The broad differential for masses in this region includes cysts, pseudocysts (including ranulas), neoplasms, inflammatory conditions and infections 1–3. Making an accurate diagnosis can be challenging due to the broad differential, as well as the potential risk of airway compromise.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Massive mature cystic teratoma of the head and neck, masquerading as a glial choristoma, causing respiratory compromise of a neonate

Suttle

Els

2023

BMJ Case Rep

View full text Add to dashboard Cite

Glial choristoma of the head and neck is a rare, benign congenital malformation consisting of a mass of heterotopic glial cells. In cases involving the upper aerodigestive tract, this can present with upper airway obstruction. In the acute setting, this can lead to diagnostic challenges due to the broad differential, as well as the additional difficulties in obtaining appropriate imaging and tissue samples due to the potential risk of airway compromise. We present a case of a neonate born with a large heterogenous mass involving the upper aerodigestive tract and multiple deep neck spaces which resulted in upper airway compromise requiring emergency surgical intervention in the form of a paediatric tracheostomy. We will discuss the histological findings which initially suggested a glial choristoma, work-up and treatment of this patient with the aim of supplementing the limited existing clinical knowledge of this congenital anomaly and understanding the implications of a paediatric tracheostomy in our setting.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Massive mature cystic teratoma of the head and neck, masquerading as a glial choristoma, causing respiratory compromise of a neonate

Suttle

Els

2023

BMJ Case Rep

View full text Add to dashboard Cite

show abstract

“…Abnormal migration of olfactory bulb glial cells then leads to glial heterotopia [ 8 ]. There are mature and immature types of ectopic glia, which are mainly composed of neurons, meningeal tissue, choroid tissue, and ependymal epithelial cells in different proportions [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Fetal pharyngeal glial heterotopia manifested as polyhydramnios: a rare case with difficult prenatal diagnosis

Cai

Wang

et al. 2023

BMC Pregnancy Childbirth

View full text Add to dashboard Cite

Background Glial heterotopia is a rare congenital developmental malformation that presents as tumor-like lesions of the nerve tissue that grow outside the nervous system, but are not true tumors. At present, most cases are reported in neonates and children and are very rarely found in fetuses. The present report describes a case of fetal pharyngeal glial heterotopia and associated imaging findings to better understand the disease in the future. Case presentation A 32-year-old pregnant woman was admitted to the hospital with polyhydramnios. An ultrasound examination revealed a hypoechoic mass in the neck of the fetus. Magnetic resonance imaging showed a well-defined mass with significant compression of the esophagus and airway. The amniotic fluid index was approximately 40 cm. Considering that difficulty swallowing and breathing may occur due to compression by the mass after birth, tracheotomy and mass resection should be performed immediately. The difficulty of the tumor resection procedure and the nature of the tumor are both factors affecting the prognosis of the fetus. The pregnant woman eventually chose to induce labor. The fetal pharyngeal mass was then resected and its pathological examination indicated pharyngeal glial heterotopia. Conclusions Polyhydramnios due to pharyngeal glial heterotopia is extremely rare and accurate prenatal diagnosis is challenging. Clinical diagnosis of glial heterotopia in preterm fetuses is difficult. Therefore, understanding glial heterotopia is helpful to improve clinical treatment options.

show abstract

A case of glial choristoma of the tongue treated with partial resection after long-term observation

Kirikoshi

Kondo

Yamanishi

et al. 2023

Journal of Oral and Maxillofacial Surgery, Medicine, and Pathol

View full text Add to dashboard Cite

Glial choristoma of the tongue. Clinicopathological analysis of a case and pathogenetic insights

Cited by 5 publications

References 42 publications

Massive mature cystic teratoma of the head and neck, masquerading as a glial choristoma, causing respiratory compromise of a neonate

Massive mature cystic teratoma of the head and neck, masquerading as a glial choristoma, causing respiratory compromise of a neonate

Fetal pharyngeal glial heterotopia manifested as polyhydramnios: a rare case with difficult prenatal diagnosis

A case of glial choristoma of the tongue treated with partial resection after long-term observation

Contact Info

Product

Resources

About