2016
DOI: 10.1002/cncr.30023
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Glioblastoma in the Canton of Zurich, Switzerland revisited: 2005 to 2009

Abstract: BACKGROUND A population‐based analysis of patients with glioma diagnosed between 1980 and 1994 in the Canton of Zurich in Switzerland confirmed the overall poor prognosis of glioblastoma. To explore changes in outcome, registry data were reevaluated for patients diagnosed between 2005 and 2009. METHODS Patients with glioblastoma who were diagnosed between 2005 and 2009 were identified by the Zurich and Zug Cancer Registry. The prognostic significance of epidemiological and clinical data, isocitrate dehydrogena… Show more

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Cited by 83 publications
(47 citation statements)
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“…Diffuse gliomas are the most common types of primary brain tumors [1]. Due to their infiltrative growth pattern they cannot be cured [2], and the median survival is up to approximately 15 years for patients with low-grade glioma (LGG) [3] and 10-12 months for patients with high-grade glioma (HGG) [4,5]. The incurable nature of diffuse gliomas thus makes preservation of quality of life a paramount factor to consider in treatment decision making.…”
Section: Introductionmentioning
confidence: 99%
“…Diffuse gliomas are the most common types of primary brain tumors [1]. Due to their infiltrative growth pattern they cannot be cured [2], and the median survival is up to approximately 15 years for patients with low-grade glioma (LGG) [3] and 10-12 months for patients with high-grade glioma (HGG) [4,5]. The incurable nature of diffuse gliomas thus makes preservation of quality of life a paramount factor to consider in treatment decision making.…”
Section: Introductionmentioning
confidence: 99%
“…Glioblastoma is the most common primary brain tumor, with an annual incidence of 3.9 cases per 100,000 individuals in the Canton of Zurich ( 1 ) and the most aggressive among all gliomas. The standard of care includes radiotherapy plus concomitant and maintenance temozolomide chemotherapy (TMZ/RT→TMZ) ( 2 ), resulting in a median survival time of 16 months in clinical trial populations ( 3 ).…”
Section: Introductionmentioning
confidence: 99%
“…We appreciate the feedback of Drs. Caldarella and Barchielli concerning our recent analysis of patterns of care and outcome among patients with glioblastoma diagnosed in the Canton of Zurich, Switzerland, from 2005 to 2009 . It is reassuring to us that our colleagues also report an improvement in outcome in their catchment area.…”
mentioning
confidence: 70%