Gliomas with intratumoral abscess formation: Description of new cases, review of the literature, and the role of ^99mTC‐Leukoscan

Abstract

Abscess formation within a brain tumor is uncommon. Intrasellar or parasellar tumors are the most common neoplasms that develop such complications. Cerebral gliomas with abscesses are extremely rare. In this paper three rare cases of glioma associated with abscess formation are described. The diagnosis of brain tumor associated with abscess is particularly difficult by conventional neuroradiological studies. (99m)Tc-labeled sulesomab can be useful in the diagnosis of brain tumors with intratumoral abscesses. There are no precise guidelines for the diagnosis and treatment of cerebral gliomas associated with abscesses formation for the low number of cases reported to date. Appropriate treatment, aimed at radical surgery, and a suitable antibiotic-protocol, deferring adjuvant postoperative therapy, is associated with a more favorable outcome. A review of the pertinent literature is also performed.

Avaliação Neuropsicológica em Pacientes com Tumores Cerebrais: revisão sistemática da literatura

“…Quanto a faixa etária mais frequente foi entre 31 e 77 anos e o ambos gêneros são mencionados. Bosma et al, 2008;Campennı et al, 2015;Curey et al, 2012;Otten et al, 2012;Prabhu et al, 2010 os autores relataram déficits neuropsicológicos sem utilizar avaliações neuropsicológicas formais, somente por meio de exames de imagem (Amiez et al, 2008;Bauer et al, 2007;Baxendale et al, 2013;Bizzi et al, 2012;Blonski et al, 2012;Bosma et al, 2008;Braun et al, 2008;Campanella et al, 2008;Campennı et al, 2015;Cipolotti et al,2015;Correa, 2008;Curey et al, 2012;Fleming et al, 2014;Fliessbach et al, 2010;Gehring et al, 2009;Gennaro et al, 2006;Giovagnoli et al, 2007;Goebel et al, 2013;Huang et al, 2014;Maesawa et al, 2015;Meguins et al, 2015;Miotto et al, 2011;McDuff et al, 2013;Mu et al, 2012;Noll et al, 2014;Nomura et al, 2013;Otten et al, 2012;Prabhu et al, 2010;Ralph et al, 2010;Satoer et al, 2014;Talacchi et al, 2013) . Estas informações podem ser observadas na Tabela 1.…”

“…Quanto à localização dos tumores (Tabela 1), os estudos mostraram que os TC em cuja investigação foi utilizada avaliação neuropsicológica têm ocorrência mais frequente nos lobos temporais (n=12 estudos) e frontais (n=12estudos) (Amiez et al, 2008;Bauer et al, 2007;Baxendale et al, 2013;Bizzi et al, 2012;Braun et al, 2008;Campanella et al, 2008;Campennı et al, 2015;Cipolotti et al, 2015;Correa, 2008;Curey et al, 2012;Fleming et al, 2014;Gennaro et al, 2006;Giovagnoli et al, 2007;Huang et al, 2014;Maesawa et al, 2015;Meguins et al, 2015;Miotto et al, 2011;McDuff et al, 2013;Mu et al, 2012;Noll et al, 2014;Otten et al, 2012;Prabhu et al, 2010;Ralph et al, 2010;Satoer et al, 2014). Em apenas um dos 31 estudos o lobo parietal foi citado como tema central de investigação (Talacchi et al, 2013).…”

Meningioma with Intra- and Peritumoral Abscess

“…However, false-negative result may be obtained if the patient is on steroid therapy. 14 Meningioma with abscess should be considered in the differential diagnosis of dural-based lesions with significant perilesional edema, especially in those with a history of systemic infection. Preoperative evaluation in such patients should include echocardiography, ultrasound of the abdomen and pelvis, dental screening, and, in symptomatic patients, urine culture and ENT (ear-nose-throat) consultation for sinusitis.…”

“…Radical surgery followed by a suitable antibiotic protocol, deferring adjuvant postoperative therapy till resolution of abscess, is associated with a favorable outcome. 14…”

Modern Opportunities of Radionuclide Methods for Diagnosis of Inflammatory Processes in the Myocardium

“…This indicator is widely used for imaging the inflammation of soft tissues [61,62,63,64]. In nuclear cardiology, an attempt was previously made to use LeukoScan® for the diagnosis of endocarditis [65,66].…”