Glioperazine B, as a New Antimicrobial Agent against<i>Staphylococcus aureus</i>, and Glioperazine C: Two New Dioxopiperazines from<i>Bionectra byssicola</i>

Zheng, Chang‐Ji; Kim, Young‐Ho; Kim, Won‐Gon

doi:10.1271/bbb.70167

Cited by 11 publications

(14 citation statements)

References 9 publications

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“…Y1085 Antibacterial activity [17] Bionectin E (22) Bionectria sp. Y1085 Antibacterial activity [17] 3,6-Bis(methylthio)-cyclo(a lanyltryptophyl) (23) Nectria inventa Trypanocidal activity [18] Chaetocin (24) Nectria inventa Trypanocidal activity [18] Chetoseminudin B (25) Nectria inventa Trypanocidal activity [18] Clonocoprogen A (26) Clonostachys compactiuscula…”

Section: Linear Oligopeptidesmentioning

confidence: 99%

“…Bionectria byssicola F120 Antimicrobial activity [25] Glioperazine C (45) Bionectria byssicola F120 - [25] Haematocin (46) Nectria haematococca Antifuangl activity [26] Lasiodipline D (47) Bionectria sp. Y1085 - [17] Sch52900 (48) Gliocladium roseum 1A Antinematodal activity [23] Sch52901 (49) Gliocladium roseum 1A Antinematodal activity [23] Verticillin A (50) Gliocladium roseum 1A Antinematodal activity [23] Bionectria sp.…”

Section: Ymf100133mentioning

confidence: 99%

“…Y1085 - [17] 11′-Deoxyverticillin A (51) Gliocladium roseum 1A Antinematodal activity [23] 11,11′-Dideoxyverticillin A (52) Bionectria sp. Y1085 - [17] Verticillin B (53) Nectria inventa Trypanocidal activity [18] Verticillin D (54) Bionectria byssicola F120 - [16] Bionectria ochroleuca Cytotoxic activity [4] Clonostachys rosea Cytotoxic activity [11] Verticillin G (55) Bionectria byssicola F120 Antibacterial activity [25] Verticillin H (…”

Section: Ymf100133mentioning

confidence: 99%

“…Four diketopiperazines: 3,6-bis(methylthio)-cyclo(alanyltryptophyl) (23), chaetocin (24), chetoseminudin B (25) and verticillin B (53) from deep water marine-derived fungus Nectria inventa showed trypanocidal activity on Trypanosoma brucei [18].…”

Section: Piperazinesmentioning

confidence: 99%

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Metabolites from Clonostachys Fungi and Their Biological Activities

Han

Zhang

et al. 2020

JoF

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Clonostachys (teleomorph: Bionectria) fungi are well known to produce a variety of secondary metabolites with various biological activities to show their pharmaceutical and agrochemical applications. Up to now, at least 229 secondary metabolites, mainly including 84 nitrogen-containing metabolites, 85 polyketides, 40 terpenoids, and 20 other metabolites, have been reported. Many of these compounds exhibit biological activities, such as cytotoxic, antimicrobial, antileishmanial, antimalarial activities. This mini-review aims to summarize the diversity of the secondary metabolites as well as their occurrences in Clonostachys fungi and biological activities.

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Section: Linear Oligopeptidesmentioning

confidence: 99%

Section: Ymf100133mentioning

confidence: 99%

Section: Ymf100133mentioning

confidence: 99%

Section: Piperazinesmentioning

confidence: 99%

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Metabolites from Clonostachys Fungi and Their Biological Activities

Han

Zhang

et al. 2020

JoF

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“…yielded bionectriol A and TMC-151 which are both metabolites of polyketide origin [12,13]. Furthermore, piperazine derivatives bionectines A–C, glioperazine B and C and verticillin G were also reported from Bionectra byssicola [14,15,16]. In the present study we provide a comprehensive analysis of natural products produced by Bionectria ochroleuca and report on two new peptides designated pullularins E ( 1 ) and F ( 2 ), and two known congeners pullularins A ( 3 ) and C ( 4 ) [17], in addition to the fungal epipolythiodioxopiperazine metabolite verticillin D ( 5 ) [18].…”

Section: Introductionmentioning

confidence: 99%

Pullularins E and F, Two New Peptides from the Endophytic Fungus Bionectria ochroleuca Isolated from the Mangrove Plant Sonneratia caseolaris

et al. 2012

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Chemical investigation of the EtOAc extract of the endophytic fungus Bionectria ochroleuca, isolated from the inner leaf tissues of the plant Sonneratia caseolaris (Sonneratiaceae) from Hainan island (China), yielded two new peptides, pullularins E and F (1 and 2) together with three known compounds (3–5). The structures of the new compounds were unambiguously determined on the basis of one- and two-dimensional NMR spectroscopy as well as by high-resolution mass spectrometry. The absolute configurations of amino acids were determined by HPLC analysis of acid hydrolysates using Marfey’s method. The isolated compounds exhibited pronounced to moderate cytotoxic activity against the mouse lymphoma cells (L5178Y) with EC50 values ranging between 0.1 and 6.7 µg/mL.

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Cladosporioles A and B, Two New Indole Derivatives from the Deep‐Sea‐Derived Fungus Cladosporium cladosporioides 170056

Zou

Chen

et al. 2022

Chemistry & Biodiversity

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Two new (cladosporioles A and B, 1 and 2) and fourteen known (3–16) compounds were isolated from the deep‐sea‐derived fungus Cladosporium cladosporioides 170056. The relative structures of the new compounds were elucidated mainly by detailed analysis of their NMR and HR‐ESI‐MS spectroscopic data. Their absolute configurations were determined by comparison of the experimental and calculated electronic circular dichroism (ECD) spectra. All isolates were tested for antimicrobial activity against Vibrio parahaemolyticus. Compound 15 exhibited weak effect with the MIC value of 156.25 μg/mL.

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Glioperazine B, as a New Antimicrobial Agent againstStaphylococcus aureus, and Glioperazine C: Two New Dioxopiperazines fromBionectra byssicola

Cited by 11 publications

References 9 publications

Metabolites from Clonostachys Fungi and Their Biological Activities

Metabolites from Clonostachys Fungi and Their Biological Activities

Pullularins E and F, Two New Peptides from the Endophytic Fungus Bionectria ochroleuca Isolated from the Mangrove Plant Sonneratia caseolaris

Cladosporioles A and B, Two New Indole Derivatives from the Deep‐Sea‐Derived Fungus Cladosporium cladosporioides 170056

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