Global, 3‐dimensional approach to natural rejuvenation: part 1 – recommendations for volume restoration and the periocular area

Raspaldo, Hervé; Gassia, V.; Niforos, Francois-Rene; Michaud, Thierry

doi:10.1111/jocd.12003

Cited by 37 publications

(34 citation statements)

References 35 publications

(152 reference statements)

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“…Restylane Vital Skinbooster is a stabilized nonanimal-based HA designed for skin hydration and rejuvenation. It was developed to meliorate skin structure, restore its hydrobalance, and improve elasticity [7][8][9] . LPOA has an extraordinarily slim dermis, composed of loose connective tissues virtually absent in the pretarsal, lateral, and medial eyelids ligaments, adhering to the fibrous underlying structure.…”

Section: Discussionmentioning

confidence: 99%

Lower periorbital area treatment with Restylane Vital Skinbooster

et al. 2016

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Facial aging along the periocular area has led to the development of new non-surgical therapies. The lower periorbital area (LPOA) is a vital region for facial rejuvenation and several procedures have been studied to treat it, especially procedures with dermal fillers for volume rebuilding. This manuscript aims to describe a filling technique with hyaluronic acid (HA) along the superficial layer of the lower periorbital area, presenting its effectiveness and safety. Our assessment was made by autonomous observers with pictures of before and after treatment, rated from 0 (no enhancement) to 100 (maximum enhancement). Patients' self-assessment was also performed using a visual analog scale (VAS) based on a 100-mm ruler affording a 0-100 rating. Thirty patients were enrolled in this study. The autonomous observers' evaluation presented a 78.4 mean improvement rate. Patients' self-assessments after the treatment were 0% reporting no improvement, 6.7% mild improvement, 23.3% moderate improvement, 66.7% great improvement, and 3.3% maximum improvement. Restylane Vital Skinbooster infiltration at the lower periorbital area proved to be a safe treatment. The described technique is also simple to execute, has a low rate of complications, and produces a high satisfaction rate.

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Section: Discussionmentioning

confidence: 99%

Lower periorbital area treatment with Restylane Vital Skinbooster

et al. 2016

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“…Facial changes that come with age are the result of the combined effects of soft tissue atrophy and loss of facial volume, gravitational factor and reduction of elastic tissue with presence of skin flaccidity, formation of rhytides, loss of muscle tone and progressive bone resorption [1][2][3]. These changes are potentiated by tobaccoism, more exposure to sun, nutritional factors, among others.…”

Section: Introductionmentioning

confidence: 99%

“…The restoration of facial volume with fillers is indicated in facial aging treatment, as well as in facial traumas, acne scars, genetic lipoatrophies or lipoatrophies associated to antiretroviral treatment in Acquired Immunodeficiency Syndrome [1][2][3].…”

Section: Introductionmentioning

confidence: 99%

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Injectable Polyethylene Glycol Gel as Dermal Filler: 01 Year Clinical and Ultrasound Follow-Up

Addor¹,

Neri²

2016

J Clin Exp Dermatol Res

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Facial alterations that occur with aging are result of combined effects of soft tissue atrophy with loss of facial volume, gravitational factor and decrease of elastic tissue. In order to minimize these alterations, minimally invasive procedures such as cutaneous filling have been gaining space in clinical practice. In 2008, Scientech CorporationItalia introduced hydrogel of polyethylene glycol (PEG) REMAKE ® as cutaneous filler. This prospective study was developed to prove the effectiveness, safety and durability over the 12 months after the application of PEG hydrogel, commercialized under the name of REMAKE ® . 40 female volunteers were included, between 30 and 60 years, with signs of malar region volume loss between 2 and 3 (Raspaldo's classification) and Nasogenian furrow accentuation, with score between 2 and 3 (Day and collaborators' classification). No patient had carried out procedures of temporary filling for 1 year or permanent filling at any time. Objective parameters always show the scale of the improvement and an evaluation was selected through ultrasound exams and surface scan for evaluation of size and depth of wrinkles improvement. Evaluations by the US were carried out for 30, 120 and 360 days of product use, in a pilot group of 18 patients randomly selected to measure the product in the application plan and numerically assess alterations of volume (absorption/migration). Its durability of up to 01 year after application is proved when no significant reduction.

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“…• Correction of nasolabial folds (NLFs) can be accomplished using injectable hyaluronic acid (HA) gels to provide volume and restore the natural 3-dimensional contour of the targeted area 1,2 • Juvéderm Vollure™ XC (17.5 mg/mL; Allergan plc, Dublin, Ireland) belongs to a family of versatile, highly moldable HA gels based on the Vycross ® technology platform (Allergan plc, Dublin, Ireland), which combines low-and high-molecular-weight HA to improve the crosslinking efficiency of the HA chains 3 • The tightly crosslinked HA network yields a gel with greater lift capacity and improved response durability 3,4 • Lidocaine is included in the Vollure XC formulation to reduce the need for conventional anesthetics during the procedure 3,5 • The objective of the present study was to investigate the safety and effectiveness of Vollure XC for the long-term correction of moderate to severe NLFs through 18 months and at 1 month after repeat treatment…”

Section: Introductionmentioning

confidence: 99%

Juvederm Vollure XC is Safe and Effective for Long-Term Correction of Nasolabial Folds: Results from a Multicenter, Randomized, Controlled Study

Dayan¹,

Maas²,

Grimes³

et al. 2017

J of Skin

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Study Objective: To evaluate Juvéderm Vollure™ XC, a hyaluronic acid (HA) gel (17.5 mg/mL) based on the Vycross ® technology platform, for long-term correction of moderate to severe nasolabial folds (NLFs).Design: This was a prospective, randomized, within-subject-controlled study.Method: Subjects (N=123) received Vollure XC initial/touch-up treatment in 1 NLF and control HA filler in the contralateral NLF. Effectiveness endpoints for Vollure XC included NLF Severity Scale (NLFSS) responder rates (≥1-point improvement vs baseline) through Month 18 after initial/touch-up treatment and at 1 month after optional repeat treatment. Additional effectiveness endpoints included subject-assessed Appraisal of Nasolabial Folds (FACE-Q; 0-100 scale) through Month 18 after initial/touch-up treatment and subject satisfaction on an 11-point scale (0=completely dissatisfied; 10=completely satisfied) through Month 18 after initial/touch-up treatment and at 1 month after repeat treatment. Injection site responses (ISRs) were assessed. Results:After initial/touchup treatment, Vollure XC responder rates were 93% at Months 1, 3, and 6, 85% at Month 9, decreased to 59% at Month 18, and increased to 94% at 1 month after repeat treatment. Improvement in mean FACE-Q scores over 18 months versus baseline showed continued benefit of Vollure XC from the subject perspective; at Months 3, 6, 12, and 18, FACE-Q scores were 70, 73, 58, and 50, respectively, versus baseline score of 32. Subjects reported a high level of satisfaction with Vollure XC throughout the study, with 82% of subjects very satisfied with treatment at Month 6, 76% at Month 12, 68% at Month 18, and 94% at 1 month after repeat treatment. Common ISRs during initial treatment with Vollure XC were firmness (89%), swelling (86%), and tenderness to touch (84%). Most ISRs were mild or moderate in severity. Conclusion:Treatment with Vollure XC was safe and effective for correcting moderate to severe NLFs, with results lasting through 18 months in over 50% of subjects.

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Global, 3‐dimensional approach to natural rejuvenation: part 1 – recommendations for volume restoration and the periocular area

Abstract: Practical guidance is provided for midfacial volume restoration and rejuvenation of the periocular area based on validated expert consensus recommendations. This will help esthetic facial physicians to achieve optimum outcomes.

Cited by 37 publications

References 35 publications

Lower periorbital area treatment with Restylane Vital Skinbooster

Lower periorbital area treatment with Restylane Vital Skinbooster

Injectable Polyethylene Glycol Gel as Dermal Filler: 01 Year Clinical and Ultrasound Follow-Up

Juvederm Vollure XC is Safe and Effective for Long-Term Correction of Nasolabial Folds: Results from a Multicenter, Randomized, Controlled Study

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