Ischemic heart disease morbidity and mortality are closely related to global and regional left ventricular function. The evaluation of left ventricular global function is a relevant part in the evolution of ischemic heart disease because it plays a significant role in prognosis prediction and patient management after revascularization. Regional function is also a critical part of the evolution, offering a possible and reliable mode for the assessment of myocardial disease. Currently several techniques for the evaluation of left ventricular parameters and function are in use. In this review we will discuss and compare currently available methods for the evaluation of global and regional left ventricular function such as 2D and 3D echocardiography, 3D speckle-tracking echocardiography, multi-slice computed tomography, and cardiac magnetic resonance imaging.Keywords: ischemic heart disease, echocardiography, 3D speckle-tracking echocardiography, multi-slice computed tomography, cardiac magnetic resonance imaging REVIEW DOI: 10.1515/jim-2017-0020 CARDIOLOGY // IMAGING Ischemic heart disease is the leading cause of death around the world. The morbidity and mortality rates are closely associated to regional and global left ventricular function in these patients. 1,2 The evaluation of global left ventricular (LV) function with noninvasive imaging tools has an important role in the therapeutic management and prognosis of patients with ischemic cardiac diseases. Several parameters have been proposed as illustrative for global left ventricular function such as volumes, ejection fraction, dimensions, end-diastolic pressure, contractility, and deformation parameters. Global systolic function is most often evaluated by measuring the difference in the end-diastolic and end-systolic volumes, determined in one, two and three dimensions, divided by the adequate end-diastolic volume. 3 Echocardiography is the most frequently used noninvasive technique for the analysis of LV parameters and function because of its accessibility, portability, and widely validated scale.