2022
DOI: 10.1101/2022.04.27.489791
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Global brain health modulates the impact of lesion damage on post-stroke sensorimotor outcomes

Abstract: Sensorimotor performance after stroke is strongly related to focal injury measures such as corticospinal tract lesion load. However, the role of global brain health is less clear. Here, we examined the impact of brain age, a measure of neurobiological aging derived from whole brain structural neuroimaging, on sensorimotor outcomes. We hypothesized that stroke lesion damage would result in older brain age, which would in turn be associated with poorer sensorimotor outcomes. We also expected that brain age would… Show more

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