Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections

Abstract

This report supports earlier predictions of the epidemic nature of diabetes in the world during the first quarter of the 21st century. It also provides a provisional picture of the characteristics of the epidemic. Worldwide surveillance of diabetes is a necessary first step toward its prevention and control, which is now recognized as an urgent priority.

Prevalence, incidence and mortality of type 2 diabetes mellitus revisited: A prospective population-based study in The Netherlands (ZODIAC-1)

“…This is the case for both the overall prevalence [6,21] and for the prevalence in all different age categories [11,[22][23][24]. Incident cases explain a part of the rise in prevalence.…”

Anti-diabetic activity of stigmasterol from soybean oil by targeting the GLUT4 glucose transporter

“…Excessive blood glucose, which is often seen as the main characteristic of DM, is sometimes accompanied by lipids and protein metabolism disorder [2]. With the rapid development of society and changes in people’s lifestyle, DM has become the third biggest threat to human health after cardiovascular and neoplastic diseases, according to the World Health Organization (WHO) [3]. There are two types of diabetes: type 1 diabetes (insulin-dependent) and type 2 diabetes (non-insulin-dependent).…”

ADVANCE: action in diabetes and vascular disease

“…1 Individuals with Type II diabetes have markedly increased risks of both macrovascular disease (including coronary heart disease and stroke) and microvascular disease (including nephropathy and retinopathy). 2,3 Globally, coronary disease is the commonest cause of death among subjects with diabetes 1 while in high-income countries diabetes is the leading cause of blindness and end-stage renal disease.…”

“…3 While the burden of diabetes is increasing throughout the world, it is doing so most rapidly in low-and middle-income countries. 1,3 Furthermore, the medical costs of managing diabetes and its consequences are high and rising: total medical expenditure on patients with diabetes in the USA in 1999 was four times greater than expenditure in people without diabetes. 4 The management of Type II diabetes and the prevention of its complications is a high priority for public health authorities in all nations.…”