Global burden of female breast cancer and its association with socioeconomic development status, 1990–2044

Abstract

BackgroundBreast cancer is a widespread disease in women worldwide.AimWe aimed to explore the global epidemiological trends of female breast cancer (FBC) between 1990 and 2044.Methods and ResultsDisease burden, population, and socio‐demographic index (SDI) data were obtained from the Global Health Data Exchange (GHDx) database. We analyzed temporal trends, age differences, risk factors, and geographic patterns of FBC disease burden globally and explored the association between age‐standardized incidence rate (ASIR) of FBC and SDI. Bayesian age‐period‐cohort model was also performed to predict the changes in FBC incidence worldwide from 2020 to 2044. First, the global ASIR of FBC increased by 14.31% from 1990 to 2019 (95% Uncertainty Interval 4.75% to 23.98%). The death rate presented a falling trend. Second, alcohol use is the most‐highlighted risk factor for FBC in some high‐income regions such as Europe. A high fasting plasma glucose levels is the most prominent risk factor for FBC in Latin America and Africa. Third, the ASIR of the FBC increases with the SDI. Fourth, the incidence is expected to increase faster among women aged 35–60 years and fastest for those aged 50–54 years from 2020 to 2044. Countries with a high incidence of FBC that is expected to increase significantly include Barbados, Burkina Faso, Senegal, Monaco, Lebanon, Togo, and Uganda.ConclusionThe disease burden of FBC varies worldwide; the findings suggest attaching importance to the control of middle and low‐middle SDI regions. Public health as well as cancer prevention experts should pay more attention to regions and populations at an increased risk of developing FBC, focusing on their prevention and rehabilitation while conducting further epidemiological studies to investigate the risk factors of their increase.

Dual Role of Alchemilla vulgaris L. Extract in Breast Cancer Regression: Reestablishment of Effective Immune Response

“…Until recently, lung cancer was considered the most commonly diagnosed type of cancer; however, in 2020, around 2.26 million new cases of breast cancer were recorded, surpassing the number of new lung cancer cases and accounting for 11.7% of all reported cancer cases [1]. As it is a multifactorial disease, various factors such as genetic factors, population structure, environment, and Pharmaceuticals 2024, 17, 286 2 of 22 lifestyle contribute to its occurrence [2,3]. The worldwide prevalence of breast cancer has risen due to changes in risk factors [4].…”

Detection of Cardiotoxicity Using Right Ventricular Free Wall Longitudinal Strain in Low Cardiovascular Risk Breast Cancer Patients Receiving Low-Dose Anthracycline Treatment

“…Breast cancer, a global concern affecting women, has seen increased incidence but reduced mortality, credited to early detection and treatment advances [1][2][3]. However, these treatments reveal diverse chemotherapy-related side effects [4].…”

Role of the intestinal microbiota and diet in the onset and progression of colorectal and breast cancers and the interconnection between both types of tumours

“…In addition, in BC, variables concerning women’s reproductive history, such as the age at menarche and at first birth, parity, breast density, chest irradiation, breastfeeding habits, and use of oral contraceptives, have an impact on disease development [ 23 , 24 ] . The effect of the body mass index (BMI) on the risk of developing BC changes according to women’s reproductive status.…”

“…The effect of the body mass index (BMI) on the risk of developing BC changes according to women’s reproductive status. While the postmenopausal years are directly related to an increased risk, in the childbearing years, the tendency is slightly protective [ 24 ] .…”