Global cardiovascular risk management in different Italian regions: An analysis of the evaluation of final feasible effect of control training and ultra sensitisation (EFFECTUS) educational program

Ferrucci, Andrea; Guida, Pietro; Corsini, Alberto; Avogaro, Angelo; Comaschi, Marco; Cortese, Claudio; Giorda, Carlo; Manzato, Enzo; Medea, Gerardo; Mureddu, Gian Francesco; Titta, Giulio; Ventriglia, Giuseppe; Riccardi, Gabriele; Zito, Giovanni; Volpe, Massimo

doi:10.1016/j.numecd.2010.10.009

Cited by 14 publications

(38 citation statements)

References 28 publications

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“…[11] In contrast, diastolic blood pressure levels were higher in those resident in central and southern areas than those recorded in northern patients (p < 0.001). [11] No significant differences were found among different subgroups with regard to HbA 1c levels, while fasting glucose levels were significantly higher in outpatients followed in southern areas than in patients followed in central and northern regions.…”

Section: Impact Of Geographic Location Of Practice On Global Cardiovamentioning

confidence: 73%

“…[11] Prevalence of major cardiovascular risk factors, including obesity, smoking habit, physical inactivity, hypertension, dyslipidaemia and diabetes, was higher in outpatients followed by physicians operating in southern areas compared with those followed in northern and central areas (p < 0.001 for trend) [ figure 2]. In contrast, cerebral and peripheral vascular artery diseases, previous myocardial infarction, transient ischaemic attack or stroke, and coronary revascularization procedures (i.e.…”

Section: Impact Of Geographic Location Of Practice On Global Cardiovamentioning

confidence: 99%

“…[9] The EFFECTUS (Evaluation of Final Feasible Effect of Control Training and Ultra Sensitisation) programme was developed to evaluate the influence of an educational intervention on the knowledge and clinical habits of Italian physicians, including GPs, cardiologists and diabetologists, distributed throughout Italy. [10] Several analyses from this database have become available, demonstrating the relatively high prevalence of major cardiovascular risk factors and associated clinical conditions in Italian outpatients, irrespective of the clinical settings [10] or geographic locations [11] in which they were followed. In addition, differences in the clinical management of cardiovascular risk factors have been described among physicians who use conventional rather than electronic support for clinical data collection and registration.…”

Section: Introductionmentioning

confidence: 99%

“…In addition, differences in the clinical management of cardiovascular risk factors have been described among physicians who use conventional rather than electronic support for clinical data collection and registration. [12] Finally, a significant increase in the proportion of patients treated according to recommendations from international guidelines was observed in those physicians who dedicated more attention to recording clinical data of their outpatients. [13] The present manuscript provides an overview of the main findings of the baseline observation of the EFFECTUS database, which allows a closer analysis of preferences and attitudes of Italian physicians.…”

Section: Introductionmentioning

confidence: 99%

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An Analysis of the Management of Cardiovascular Risk Factors in Routine Clinical Practice in Italy

Ferrucci

Guida

Avogaro

et al. 2011

High Blood Pressure & Cardiovascular Prevention

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Cardiovascular diseases represent the leading cause of morbidity and mortality, worldwide. Early detection and appropriate management of cardiovascular risk factors and disease markers in daily clinical practice may improve preventive strategies and reduce the burden of cardiovascular disease. The EFFECTUS (Evaluation of Final Feasible Effect of Control Training and Ultra Sensitisation) programme was an educational programme aimed at evaluating prevalence of major cardiovascular risk factors among outpatients, and preferences and attitudes for cardiovascular disease management among Italian physicians in their routine clinical practice. This article provides an overview of the main findings of different analyses from the EFFECTUS database, which have demonstrated a high prevalence of cardiovascular risk factors, irrespective of the clinical settings and outpatient clinics in which patients were followed. Also, findings from this database suggest that more intensive clinical data recording was paralleled by better adherence to guidelines, and that use of electronic rather than conventional support for clinical data collection and registration improved accuracy in data recording, which translated into better management of patients at risk in daily clinical practice.

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Section: Impact Of Geographic Location Of Practice On Global Cardiovamentioning

confidence: 73%

Section: Impact Of Geographic Location Of Practice On Global Cardiovamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

An Analysis of the Management of Cardiovascular Risk Factors in Routine Clinical Practice in Italy

Ferrucci

Guida

Avogaro

et al. 2011

High Blood Pressure & Cardiovascular Prevention

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“…Previous work has shown that the lipidemic parameters affecting cardiovascular risk are influenced by geographical gradient. 5,6 One of the advantages of integrating data from different population studies is the use of regional data to cover the entire national territory.…”

Section: Introductionmentioning

confidence: 99%

Development of a Pilot Project on Data Sharing among Partners of the Italian Hub of Population Biobanks (HIBP): Association between Lipid Profile and Socio-Demographic Variables

Napolitano

Santoro

Puopolo

et al. 2014

Biopreservation and Biobanking

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The Italian Hub of Population Biobanks (HIBP) includes both ongoing and completed studies that are heterogeneous in both their purpose and in the specimens collected. The heterogeneity in starting conditions makes sharing study data very difficult because of technical, ethical, and collection rights issues that hamper collaboration and synergy. With the aim of overcoming these difficulties and establishing the "proof-of-concept" that sharing studies is achievable among Italian collections, a data-sharing pilot project has been agreed to by HIBP members. Participants agreed to the general methodology and signed a shared Data Transfer Agreement. The biobanks involved were: EURAC (Micros study), CIG (GEHA project), CNESPS (FINE, MATISS, MONICA, OEC1998, ITR (Italian Twin Register), and IPREA studies, and MOLIBANK (Moli-Sani project). Biobank data were uploaded into a common database using a dedicated informatics infrastructure. Demographic data, and anthropometric and hematochemical parameters were shared for each record. Each biobank uploaded into the common database a dataset with a minimum of 1000 subjects, for a total of 5071 records. After a harmonization process, the final dataset included 3882 records. Subjects were grouped into three main geographic areas of Italy (North, Center, and South) and separate analyses were performed for men and women. The 3882 records were analyzed through multivariate logistic regression analysis. Results were expressed as odds ratios with 95% confidence interval. Results show several geographical differences in the lipidemic pattern, mostly regarding cholesterol-HDL, which represents a strong basis for further, deeper sample-based studies. This HIBP pilot study aimed to prove the feasibility of such collaborations and it provides a methodological prototype for future studies based on the participation in the partnership of well-established quality collections.

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Impact of Diabetes Mellitus on the Clinical Management of Global Cardiovascular Risk: Analysis of the Results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitization (EFFECTUS) Educational Program

Ferrucci¹,

Guida

Avogaro

et al. 2011

Clinical Cardiology

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Background: The Evaluation of Final Feasible Effect of Ultra Control Training and Sensitization (EFFECTUS) study is aimed at implementing global cardiovascular (CV) risk management in Italy. Hypothesis: To evaluate the impact of diabetes mellitus (DM) on attitudes and preferences for clinical management of global CV risk among physicians treating diabetic or nondiabetic patients. Methods: Involved physicians were asked to submit data into a study-designed case-report form, covering the first 10 adult outpatients consecutively seen in May 2006. All available clinical data were centrally analyzed for global CV risk assessment and CV risk profile characterization. Patients were stratified according to the presence or absence of DM. Results: Overall, 1078 physicians (27% female, ages 50 ± 7 y) collected data of 9904 outpatients (46.5% female, ages 67 ± 9 y), among whom 3681 (37%) had a diagnosis of DM at baseline. Diabetic patients were older and had higher prevalence of obesity, hypertension, dyslipidemia, and associated CV diseases than nondiabetic individuals (P < 0.001). They had higher systolic blood pressure, total cholesterol, triglycerides, and creatinine levels, but lower high-density lipoprotein cholesterol levels than nondiabetic patients (P < 0.001). Higher numbers of blood pressure and lipid-lowering drugs and antiplatelet agents were used in diabetic than in nondiabetic patients (P < 0.001). Conclusions: The EFFECTUS study confirmed higher CV risk and more CV drug prescriptions in diabetic than in nondiabetic patients. Presence of DM at baseline significantly improved clinical data collection. Such an approach, however, was not paralleled by a better control of global CV risk profile, which was significantly worse in the former than in the latter group. Introduction Diabetes mellitus (DM) affects approximately 100 million persons worldwide. In view of the increasing prevalence of unfavorable lifestyle habits (eg, smoking, physical inactivity, and high-caloric diet) and associated clinical conditions (obesity, atherogenic dyslipidemia, and hypertension), it is likely that its incidence will further and dramatically rise in both Western and developing countries in the next decades.Nowadays, both general practitioners and specialized physicians are encountering many of these patients in their routine clinical practice, thus having the opportunity to substantially reduce the global burden of disease related to DM and glucose abnormalities. 1,2 Diabetic patients have, in fact, higher susceptibility than nondiabetic individuals to develop major cardiovascular (CV) events, such as myocardial infarction, stroke, and CV death, and non-CV mortality. 3,4 Because CV diseases represent the main causes of death and disability in people with DM, physicians must recognize the key role of this clinical condition to promptly stratify and timely treat these patients. Evidence has, in fact, demonstrated that a therapeutic approach based on global CV risk management may effectively reduce the burden of CV disease in diabet...

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Global cardiovascular risk management in different Italian regions: An analysis of the evaluation of final feasible effect of control training and ultra sensitisation (EFFECTUS) educational program

Cited by 14 publications

References 28 publications

An Analysis of the Management of Cardiovascular Risk Factors in Routine Clinical Practice in Italy

An Analysis of the Management of Cardiovascular Risk Factors in Routine Clinical Practice in Italy

Development of a Pilot Project on Data Sharing among Partners of the Italian Hub of Population Biobanks (HIBP): Association between Lipid Profile and Socio-Demographic Variables

Impact of Diabetes Mellitus on the Clinical Management of Global Cardiovascular Risk: Analysis of the Results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitization (EFFECTUS) Educational Program

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