Global disease burden attributable to kidney dysfunction, 1990–2019: A health inequality and trend analysis based on the global burden of disease study

Yu, Yingying; Zhang, Mingyi; Tang, Yuqin; Zhai, Chunxia; Hu, Wanqin; Yu, Guanghui; Sun, Hongyu; Xu, Ying; Zong, Qiqun; Liu, Yuqi; Gong, Xingyu; Wang, Fang; Zou, Yanfeng

doi:10.1016/j.diabres.2024.111801

Diabetes Research and Clinical Practice

2024

DOI: 10.1016/j.diabres.2024.111801

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Global disease burden attributable to kidney dysfunction, 1990–2019: A health inequality and trend analysis based on the global burden of disease study

Yingying Yu,

Mingyi Zhang,

Yuqin Tang

et al.

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2024

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Short-Term Effects of NO2 Exposure on Hospitalization for Chronic Kidney Disease

Zhang,

Ruan,

Ling

2024

Toxics

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This study investigates the correlation between short-term exposure to nitrogen dioxide (NO2) and hospitalization for chronic kidney disease (CKD) in Lanzhou, China. A distributed lag nonlinear model (DLNM) was employed to examine the relationship between changes in NO2 concentration and CKD hospitalizations. Subgroup analyses were conducted to assess the sensitivity of different populations to NO2 exposure. A total of 35,857 CKD hospitalizations occurred from 1 January 2014 to 31 December 2019. The average daily concentration of NO2 was 47.33 ± 17.27 µg/m3. A significant exposure response relationship was observed between changes in NO2 concentration and the relative risk (RR) of CKD hospitalization. At lag0 (the same day) and lag0-1 (cumulative same day and the previous 1 day) to lag0-4 (cumulative same day and the previous 4 days), NO2 exhibited a harmful effect on CKD hospitalizations, with the maximum effect occurring at lag0-1. For every 10 µg/m3 increase in NO2 concentration, the RR of CKD hospitalization was 1.034 [95% confidence interval (CI): 1.017, 1.050]. Subgroup analyses revealed that the adverse effects of NO2 were more pronounced in females and individuals aged ≥65 years. The harmful effects were also more significant during the cold season. In conclusion, short-term NO2 exposure is associated with an increased relative risk of CKD hospitalization. Continuous efforts to improve air quality are essential to protect public health.

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Short-Term Effects of NO2 Exposure on Hospitalization for Chronic Kidney Disease

Zhang,

Ruan,

Ling

2024

Toxics

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Global disease burden attributable to kidney dysfunction, 1990–2019: A health inequality and trend analysis based on the global burden of disease study

Cited by 1 publication

References 52 publications

Short-Term Effects of NO2 Exposure on Hospitalization for Chronic Kidney Disease

Short-Term Effects of NO2 Exposure on Hospitalization for Chronic Kidney Disease

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