Global distribution and diversity of ovine-associated Staphylococcus aureus

Smith, Edward M.; Needs, Polly F.; Manley, Grace C A; Green, Laura

doi:10.1016/j.meegid.2013.09.008

Cited by 38 publications

(32 citation statements)

References 53 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This distribution difers from North and South America and Australia, where CC133 is the major ovine clone. Isolates from CC97 (bovineassociated), CC5, CC8 and CC30 (human-associated) were also found in this report, indicating high interspeciic transmission of these genotypes [9]. Among zoological park animals in Greece, human-associated lineages ST80, ST8 and ST15, some of them with human pulsotype by PFGE analysis, suggest human-to-animal transmission [10].…”

Section: Frontiers In Staphylococcus Aureus 180 Frontiers In Staphylosupporting

confidence: 54%

Bacteriophage Therapy: An Alternative for the Treatment of Staphylococcus aureus Infections in Animals and Animal Models

Barrera-Rivas¹,

Valle-Hurtado²,

M.González-Lugo³

et al. 2017

Frontiers in Staphylococcus Aureus

View full text Add to dashboard Cite

Staphylococcus aureus causes hospital-acquired (HA), community-acquired (CA) and companion animal and livestock-associated (LA) infections. Molecular epidemiology studies suggest that although host speciicity may be associated with speciic genetic lineages, recent human-to-animal and animal-to-human transmissions related to mobile genetic elements have been described. Gene transfers include virulence and antibiotic resistance genes, thus making it diicult to control multidrug resistance S. aureus infections. Bacteriophages (phages) and endolysins, the enzymes responsible for bacterial lysis by phages, are alternatives to the use of antibiotics for the control of S. aureus infections. In this work, we review current advances in the development of phage therapy and the study and design of recombinant endolysins to treat S. aureus infections. Preliminary results of bacteriophage isolation based on molecular epidemiology knowledge show that bacteriophages are speciic of genetic lineages and that this strategy may be used as an approach to isolate and evaluate new bacteriophages for therapy.

show abstract

Section: Frontiers In Staphylococcus Aureus 180 Frontiers In Staphylosupporting

confidence: 54%

Bacteriophage Therapy: An Alternative for the Treatment of Staphylococcus aureus Infections in Animals and Animal Models

Barrera-Rivas¹,

Valle-Hurtado²,

M.González-Lugo³

et al. 2017

Frontiers in Staphylococcus Aureus

View full text Add to dashboard Cite

show abstract

“…CC130-MSSA appears to be a common lineage in sheep and a major cause of infections in these animals (see [154], where it is named CC700), but we are not aware of observations in humans. Previously, CC130-MRSA-XI have been found in humans as well as in a wider variety of wild and domestic animals (see references quoted in the Introduction).…”

Section: Resultsmentioning

confidence: 99%

“…This strain was also frequently observed in small domestic ruminants, i . e ., goats and sheep [2,3,154], but also in domestic pigs [123], cats, dogs, [156], cattle [155] and donkeys [157]. It could have been transmitted from wild to domestic ruminants, or vice versa , and the few reported human cases [116] could be related to contact to animals or animal products.…”

Section: Resultsmentioning

confidence: 99%

Diversity of Staphylococcus aureus Isolates in European Wildlife

et al. 2016

View full text Add to dashboard Cite

Staphylococcus aureus is a well-known colonizer and cause of infection among animals and it has been described from numerous domestic and wild animal species. The aim of the present study was to investigate the molecular epidemiology of S. aureus in a convenience sample of European wildlife and to review what previously has been observed in the subject field. 124 S. aureus isolates were collected from wildlife in Germany, Austria and Sweden; they were characterized by DNA microarray hybridization and, for isolates with novel hybridization patterns, by multilocus sequence typing (MLST). The isolates were assigned to 29 clonal complexes and singleton sequence types (CC1, CC5, CC6, CC7, CC8, CC9, CC12, CC15, CC22, CC25, CC30, CC49, CC59, CC88, CC97, CC130, CC133, CC398, ST425, CC599, CC692, CC707, ST890, CC1956, ST2425, CC2671, ST2691, CC2767 and ST2963), some of which (ST2425, ST2691, ST2963) were not described previously. Resistance rates in wildlife strains were rather low and mecA-MRSA isolates were rare (n = 6). mecC-MRSA (n = 8) were identified from a fox, a fallow deer, hares and hedgehogs. The common cattle-associated lineages CC479 and CC705 were not detected in wildlife in the present study while, in contrast, a third common cattle lineage, CC97, was found to be common among cervids. No Staphylococcus argenteus or Staphylococcus schweitzeri-like isolates were found. Systematic studies are required to monitor the possible transmission of human- and livestock-associated S. aureus/MRSA to wildlife and vice versa as well as the possible transmission, by unprotected contact to animals. The prevalence of S. aureus/MRSA in wildlife as well as its population structures in different wildlife host species warrants further investigation.

show abstract

“…In the case of t1403, most were CC133-positive and the remainder were CC97-positive. Clonal complex 133 is mainly associated with sheep and goats (Guinane et al, 2010b;Porrero et al, 2012;Smith et al, 2014), but it has also been isolated from cows with IMI (Schlotter et al, 2012;Silva et al, 2013) but not from humans. The t524 strains of CLR were almost exclusively positive for CC71, a CC that has never been described as an infectious pathogen in humans or animals.…”

Section: Zoonotic Transfer Of Staph Aureus Between Cattle and Humansmentioning

confidence: 99%

Bovine Staphylococcus aureus: Subtyping, evolution, and zoonotic transfer

Boss

Cosandey

Luini

et al. 2016

Journal of Dairy Science

View full text Add to dashboard Cite

Staphylococcus aureus is globally one of the most important pathogens causing contagious mastitis in cattle. Previous studies using ribosomal spacer (RS)-PCR, however, demonstrated in Swiss cows that Staph. aureus isolated from bovine intramammary infections are genetically heterogeneous, with Staph. aureus genotype B (GTB) and GTC being the most prominent genotypes. Furthermore, Staph. aureus GTB was found to be contagious, whereas Staph. aureus GTC and all the remaining genotypes were involved in individual cow disease. In addition to RS-PCR, other methods for subtyping Staph. aureus are known, including spa typing and multilocus sequence typing (MLST). They are based on sequencing the spa and various housekeeping genes, respectively. The aim of the present study was to compare the 3 analytic methods using 456 strains of Staph. aureus isolated from milk of bovine intramammary infections and bulk tanks obtained from 12 European countries. Furthermore, the phylogeny of animal Staph. aureus was inferred and the zoonotic transfer of Staph. aureus between cattle and humans was studied. The analyzed strains could be grouped into 6 genotypic clusters, with CLB, CLC, and CLR being the most prominent ones. Comparing the 3 subtyping methods, RS-PCR showed the highest resolution, followed by spa typing and MLST. We found associations among the methods but in many cases they were unsatisfactory except for CLB and CLC. Cluster CLB was positive for clonal complex (CC)8 in 99% of the cases and typically positive for t2953; it is the cattle-adapted form of CC8. Cluster CLC was always positive for t529 and typically positive for CC705. For CLR and the remaining subtypes, links among the 3 methods were generally poor. Bovine Staph. aureus is highly clonal and a few clones predominate. Animal Staph. aureus always evolve from human strains, such that every human strain may be the ancestor of a novel animal-adapted strain. The zoonotic transfer of IMI-and milk-associated strains of Staph. aureus between cattle and humans seems to be very limited and different hosts are not considered as a source for mutual, spontaneous infections. Spillover events, however, may happen.

show abstract

Global distribution and diversity of ovine-associated Staphylococcus aureus

Cited by 38 publications

References 53 publications

Bacteriophage Therapy: An Alternative for the Treatment of Staphylococcus aureus Infections in Animals and Animal Models

Bacteriophage Therapy: An Alternative for the Treatment of Staphylococcus aureus Infections in Animals and Animal Models

Diversity of Staphylococcus aureus Isolates in European Wildlife

Bovine Staphylococcus aureus: Subtyping, evolution, and zoonotic transfer

Contact Info

Product

Resources

About