In an effort to enhance local governance and public service delivery in Ethiopia's Amhara Region, this study embarks on a comprehensive investigation into the myriad factors influencing public service delivery. It fills a critical gap in existing literature by examining the combined impact of institutional, economic, political, environmental, and legal determinants on public service efficacy. This study is significant for its in-depth exploration of local administration dynamics, vital for regional development in the socioeconomically diverse Amhara Region. Employing a quantitative methodology for a holistic view of local governance. Regression analysis used to scrutinize patterns and correlations within the data, offering an empirical understanding of various factors' influence on service provision. The findings are enlightening Institutional, economic, political and legal aspects are found to significantly and positively impact service delivery. Although environmental factors seem less significant in quantitative terms. This study advocates for integrated governance strategies that holistically encompass these various determinants. It underscores the importance of developing comprehensive policies and enhancing governance, acknowledging both overt and subtle influences on service delivery. The research contributes significantly to the field, offering in-depth insights essential for formulating inclusive, effective policies. In summary, this research provides pivotal insights into governance dynamics in the Amhara Region, offering a detailed framework for policymakers. It underscores the need for comprehensive, inclusive strategies that are crucial for improving service delivery and fostering socioeconomic development in the region. Thus, this study serves as an invaluable resource for those seeking to understand and enhance public service delivery in diverse socioeconomic contexts, offering guidance for effective governance and policy development.