Global epidemiology of community-associated methicillin resistant Staphylococcus aureus (CA-MRSA)

Detection and antibiotic resistance pattern of Staphylococcus aureusand (MRSA) isolated from healthcare workers Nares at three Gaza hospitals, Palestine

“…Fortunately, whereas HA-MRSA isolates are generally multidrug resistant, CA-MRSA tends to be resistant primarily to β-lactam antibiotics. However, recent studies indicate that many CA-MRSA lineages are becoming increasingly resistant to non β-lactam antibiotics [7], while a growing number of reports describe replacement of HA-MRSA by CA-MRSA in healthcare settings [7,8].…”

Detection of Integrons and Staphylococcal Cassette Chromosome ( SCCmec ) Types in Staphylococcus Aureus Isolated from Burn and Non-Burn Patients

“…(15,16) On the other hand, the emergence of CA-MRSA infections among burn patients has created a serious challenge in infections control process. (17) HA-MRSA and CA-MRSA can be distinguished from each other due to their SCCmec types basis, therefore SCCmec types I, II, III and VIII are mainly associated with HA-MRSA while CA-MRSA often characterized by SCCmec types IV, V, VI and VII. (18) The aim of the present study was to determine the various SCCmec types and integrons classes in S. aureus strains isolated from burn and non-burn patients.…”

The Bicomponent Pore-Forming Leucocidins of Staphylococcus aureus

“…However, the recent increase in the incidence of multidrug-resistant isolates such as hospital-acquired methicillinresistant S. aureus (HA-MRSA) and community-acquired MRSA (CA-MRSA) and the increased dominance of highly virulent clonal lineages that can cause aggressive disease have diminished the success of such therapeutic strategies (5)(6)(7)(8)(9)(10). A number of comprehensive reviews addressing the increased incidence of these infectious lineages have already been reported (5,6,(11)(12)(13). It is clear that S. aureus exhibits tremendous adaptability when confronted with aversive stimuli (i.e., antibiotics) and harsh environmental conditions (host tissues that deprive the organism of essential nutrients), allowing it to execute a highly pathogenic life-style.…”