Global estimates of the number of pregnancies at risk of malaria from 2007 to 2020: a demographic study

Reddy, Valentina; Weiss, Daniel J.; Rozier, Jennifer; Kuile, Feiko O. Ter; Dellicour, Stephanie

doi:10.1016/s2214-109x(22)00431-4

Cited by 26 publications

(14 citation statements)

References 21 publications

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“…The WHO recommend sleeping under ITN and indoor residual spraying (IRS) to prevent mosquito bites or chemoprevention (IPTp-SP) to suppress malaria infections in sub-Saharan Africa where malaria is endemic (3). The study found a significant association between malaria infection and sleeping under ITN.…”

Section: Plos Onementioning

confidence: 91%

Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study

Dwumfour,

Bam,

Owusu

et al. 2023

PLoS ONE

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Introduction Malaria in pregnancy is a global public health problem with the majority of its impact seen in sub-Saharan Africa. Pregnant women with malaria infection are at risk of adverse maternal outcomes. In Ghana, malaria in pregnancy accounts for about 17.6% of outpatient department attendance. Ashanti region is among the three regions with the highest malaria prevalence in pregnancy, particularly in the Ejisu Municipality. The study, therefore, assessed the prevalence and determinants of malaria infection among pregnant women seeking antenatal care at the Ejisu Government Hospital in Ghana. Methods A cross-sectional study design with a convenience sampling technique was used to select 140 respondents for the study. Primary data such as age and residence of respondents were collected using a questionnaire and secondary data such as gestational age and Sulphadoxine Pyrimethamine (SP) administration were collected from clients’ maternal health record booklet. Bivariate and multivariate logistic regression analysis were used to assess the association between the malaria infection and the independent variables, and a p-value of < 0.05 was considered statistically significant. Results The overall prevalence of malaria in pregnancy was 24 (17.1%). Most of the respondents had received counselling and health education 126 (90%), two or more doses of SP 95 (87.2%), Insecticide Treated Net (ITN) 99 (70.7%) and were sleeping under ITN 104 (74.3%). Multivariate logistic regression analysis showed a statistically significant association between malaria infection and sleeping under ITN (AOR = 0.05; 95% CI = 0.01–0.28, p< .001), the use of insecticide mosquito spray (AOR = 0.27; 95% CI = 0.09–0.84, p = .045) and reason for not using ITN due to the use of other preventive measures (AOR = 0.06; 95% CI = 0.01–0.61, p = .017). Conclusion There was a high prevalence of malaria infection among study respondents despite the high usage of preventive measures for malaria in this study. It is therefore crucial that stakeholders in malaria control identify effective strategies to curb malaria transmission globally.

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Section: Plos Onementioning

confidence: 91%

Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study

Dwumfour,

Bam,

Owusu

et al. 2023

PLoS ONE

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“…It is also dominant in some regions of Southeast Asia, the Western Pacific, and South America, where P. vivax and P. falciparum are the leading causes of the disease [ 1 ]. In 2020, out of 121.9 million pregnancies at risk of malaria globally, the World Health Organization (WHO) region with the highest number of pregnancies at risk of malaria was Southeast Asia, with 52.9 million pregnancies, followed by the African region with 46.1 million pregnancies, and the Eastern Mediterranean region with 11.1 million pregnancies [ 2 ]. In 2021, out of 40 million pregnancies in high-to-moderate transmission countries in SSA, nearly 13.3 million (32%) women experienced malaria infection during pregnancy [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

Spatial distribution and determinants of intermittent preventive treatment for malaria during pregnancy: a secondary data analysis of the 2019 Ghana malaria indicators survey

Ndayishimiye,

Teg-Nefaah Tabong

2024

BMC Pregnancy Childbirth

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Background Malaria during pregnancy is associated with poor maternal, foetal, and neonatal outcomes. To prevent malaria infection during pregnancy, the World Health Organization recommended the use of intermittent preventive therapy with sulfadoxine-pyrimethamine (IPTp-SP) in addition to vector control strategies. Although Ghana’s target is to ensure that all pregnant women receive at least three (optimal) doses of SP, the uptake of SP has remained low; between 2020 and 2022, only 60% of pregnant women received optimal SP during their most recent pregnancy. This study sought to map the geospatial distribution and identify factors associated with SP uptake during pregnancy in Ghana. Methods Secondary data analysis was conducted using the 2019 Ghana Malaria Indicator Survey dataset. The data analysed were restricted to women aged 15–49 years who reported having a live birth within the two years preceding the survey. A modified Poisson regression model was used to determine factors associated with SP uptake during pregnancy. Geospatial analysis was employed to map the spatial distribution of optimal SP uptake across the ten regions of Ghana using R software. Results The likelihood that pregnant women received optimal SP correlated with early initiation of first antenatal care (ANC), number of ANC contacts, woman’s age, region of residence, and family size. Overall, the greater the number of ANC contacts, the more likely for pregnant women to receive optimal SP. Women with four or more ANC contacts were 2 times (aPR: 2.16; 95% CI: [1.34–3.25]) more likely to receive optimal SP than pregnant women with fewer than four ANC contacts. In addition, early initiation and a high number of ANC contacts were associated with a high number of times a pregnant woman received SP. Regarding spatial distribution, a high uptake of optimal SP was significantly observed in the Upper East and Upper West Regions, whereas the lowest was observed in the Eastern Region of Ghana. Conclusions In Ghana, there were regional disparities in the uptake of SP during pregnancy, with the uptake mainly correlated with the provision of ANC services. To achieve the country’s target for malaria control during pregnancy, there is a need to strengthen intermittent preventive treatment for malaria during pregnancy by prioritizing comprehensive ANC services.

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“…Furthermore, in 2020, there were 248 million pregnancies worldwide, of which 157 million (63%) were registered in 85 malaria-endemic countries and 122 million (49%) occurred in areas with transmission of the parasite. In this last group, there were an estimated 1.4 million (1%) stillbirths, 33.5 million (27%) induced abortions, and 16.1 million (13%) spontaneous abortions [ 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…Some associated factors of PAM in Colombia include maternal and gestational age, number of pregnancies, parity, and previous malaria episodes; however, these factors were not consistent in research conducted in different regions of the country [ 16 ]. According to other studies the outcomes of PAM included gestational anaemia, severe malaria with liver dysfunction, acidosis or thrombocytopenia; alteration of the development of the immune response; abortion, premature birth, stillbirth, low birth weight, and lower height and head circumference at birth [ 3 , 4 , 6 , 17 – 19 ].…”

Section: Introductionmentioning

confidence: 99%

Prospective study of malaria in pregnancy, placental and congenital malaria in Northwest Colombia

Cardona-Arias,

Carmona-Fonseca

2024

Malar J

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Background Pregnancy Associated Malaria (PAM) include malaria in pregnancy (MiP), placental malaria (PM), and congenital malaria (CM). The evidence available in Colombia on PAM focuses on one of the presentations (MiP, PM or CM), and no study longitudinally analyses the infection from the pregnant woman, passing through the placenta, until culminating in the newborn. This study determined the frequency of MiP, PM, and CM caused by Plasmodium vivax, Plasmodium falciparum, or mixed infections, according to Thick Blood Smear (TBS) and quantitative Polymerase Chain Reaction (qPCR). Identifying associated factors of PAM and clinical-epidemiological outcomes in northwestern Colombia. Methods Prospective study of 431 pregnant women, their placenta, and newborns registered in the data bank of the research Group “Salud y Comunidad César Uribe Piedrahíta” which collected information between 2014 and 2020 in endemic municipalities of the departments of Córdoba and Antioquia. The frequency of infection was determined with 95% confidence intervals. Comparisons were made with the Chi-square test, Student t-test, prevalence ratios, and control for confounding variables by log-binomial regression. Results The frequency of MiP was 22.3% (4.6% using TBS), PM 24.8% (1.4% using TBS), and CM 11.8% (0% using TBS). Using TBS predominated P. vivax. Using qPCR the proportions of P. vivax and P. falciparum were similar for MiP and PM, but P. falciparum predominated in CM. The frequency was higher in nulliparous, and women with previous malaria. The main clinical effects of PAM were anaemia, low birth weight, and abnormal APGAR score. Conclusions The magnitude of infections was not detected with TBS because most cases were submicroscopic (TBS-negative, qPCR-positive). This confirmed the importance of improving the molecular detection of cases. PAM continue being underestimated in the country due to that in Colombia the control programme is based on TBS, despite its outcomes on maternal, and congenital health.

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Global estimates of the number of pregnancies at risk of malaria from 2007 to 2020: a demographic study

Cited by 26 publications

References 21 publications

Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study

Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study

Spatial distribution and determinants of intermittent preventive treatment for malaria during pregnancy: a secondary data analysis of the 2019 Ghana malaria indicators survey

Prospective study of malaria in pregnancy, placental and congenital malaria in Northwest Colombia

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