This paper is concerned with quantitative estimates for the Navier-Stokes equations.First we investigate the relation of quantitative bounds to the behaviour of critical norms near a potential singularity with Type I bound uWe demonstrate that this potential blow-up rate is optimal for a certain class of potential non-zero backward discretely self-similar solutions. Second, we quantify the result of Seregin ( 2012), which says that if u is a smooth finiteenergy solution to the Navier-Stokes equations on R 3 × (0, 1) withTo prove our results we develop a new strategy for proving quantitative bounds for the Navier-Stokes equations. This hinges on local-in-space smoothing results (near the initial time) established by Jia and Šverák ( 2014), together with quantitative arguments using Carleman inequalities given by Tao (2019).