Global Health Governance and Antimicrobial Resistance

Bennett, Belinda; Iredell, Jonathan R.

doi:10.1007/978-3-030-27874-8_24

“…The International Health Regulations (IHRs), which are legally binding instruments of international law, recognises the threat that infectious diseases pose to public health and transnational security. However, ambiguity as to how the IHRs can be applied (Bennett & Iredell, 2020), and the limited capacity of countries to fully implement them (CDC, 2019b), may, in part, contribute to the existing gaps in global preparedness for public health emergencies. There is, therefore, the need for countries to consider options that are founded on the principles of the IHRs that will enhance a countries' capacity to develop and maintain minimum capabilities to address public health threats.…”

Section: Global Health Security Agenda (Ghsa)mentioning

confidence: 99%

Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Esiovwa¹,

Connolly²,

Hursthouse³

et al. 2022

RoutledgeOpenRes

3

0

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Background: This paper examines the suitability of extant governance frameworks at an international level for addressing antimicrobial resistance (AMR), which is a creeping crisis for global health security. Methods: Our study begins by evaluating the place of antimicrobial resistance (AMR) within United Nations (UN) Sustainable Development Goals (SDG) targets and indicators. This is followed by a discussion of the global health security agenda (GHSA). We examine how AMR needs to be taken more seriously within global policy frameworks based on adopting a One Health approach. The research is supported by a systematic analysis of the national action plans for addressing AMR published by the World Health Organisation (WHO). Results: We determine that political leaders need to do more to promote the problem of AMR and that global health institutions need to invest more energy in thinking about how AMR is governed as part of an already busy global health security agenda. This includes building capacities within health systems, embedding evaluation processes, and enhancing public service leadership within this area. Conclusions: Our review of global policy frameworks and the national plans for AMR highlight the patchy coverage of AMR strategies globally and nationally. This article represents a springboard for future research including whether and to what extent a One Health approach to AMR in the environment has been implemented in practice within national health and environmental systems.

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Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Esiovwa,

Connolly,

Hursthouse

et al. 2023

RoutledgeOpenRes

1

0

View full text Add to dashboard Cite

Background: This paper examines the suitability of extant governance frameworks at an international level for addressing antimicrobial resistance (AMR), which is a creeping crisis for global health security. Methods: Our study begins by evaluating the place of antimicrobial resistance (AMR) within United Nations (UN) Sustainable Development Goals (SDG) targets and indicators. This is followed by a discussion of the global health security agenda (GHSA). We examine how AMR needs to be taken more seriously within global policy frameworks based on adopting a One Health approach. The research is supported by a systematic analysis of the national action plans for addressing AMR published by the World Health Organisation (WHO). Results: We determine that political leaders need to do more to promote the problem of AMR and that global health institutions need to invest more energy in thinking about how AMR is governed as part of an already busy global health security agenda. This includes building capacities within health systems, embedding evaluation processes, and enhancing public service leadership within this area. Conclusions: Our review of global policy frameworks and the national plans for AMR highlight the patchy coverage of AMR strategies globally and nationally. This article represents a springboard for future research including whether and to what extent a One Health approach to AMR in the environment has been implemented in practice within national health and environmental systems.

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Clinical and Antimicrobial Profile of Acinetobacter Species in Critical Care Setting- An Emerging Nosocomial Bug

Nilofar,

Mariraj,

Palanisamy

et al. 2024

Salud, Ciencia y Tecnología

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Background: The increasing prevalence of multidrug-resistant bacterial infections, particularly within healthcare-associated settings, poses a global public health threat. Among these pathogens, Acinetobacter species, notably Acinetobacter baumannii, have gained recognition as opportunistic nosocomial pathogens with a concerning propensity for antimicrobial resistance. Understanding their clinical and antimicrobial profile is crucial for addressing the challenges posed by these infections.Objectives: To assess the prevalence of Acinetobacter species in distinct clinical samples.To analyze Acinetobacter species' clinical profiles and patterns of antibiotic sensitivity using a range of clinical samples.Materials and Methods: A cross-sectional study was conducted in a tertiary care hospital in South India, approved by the Institutional Ethics Committee. Patients with confirmed Acinetobacter infections were included, and clinical samples were collected from the critical care unit. Demographics, comorbidities, clinical presentations, and outcomes were recorded. Laboratory processing included standard protocols for sample analysis, with confirmation through advanced methods such as PCR.Results: Out of 82 participants, 48.78% showed positive cultures for Acinetobacter species. Prevalence varied by sample type, with urine samples exhibiting the highest positivity (50%). Clinical analysis of 40 infected patients revealed a mean age of 43.72 ± 17.34 years. Musculoskeletal symptoms (17.5%) and obstetric complications (17.5%) were prominent clinical presentations. Antibiotic sensitivity analysis demonstrated that 51% of isolates were multidrug-resistant, with high resistance to key antibiotics. Commonly resistant antibiotics included Cefepime, Piperacillin, Levofloxacin, Imipenem, Meropenem, and Amikacin.Conclusion: This study adds to the growing understanding of Acinetobacter infections, emphasizing the need for awareness, infection control, and judicious antibiotic use. The multidisciplinary clinical presentations and high resistance rates underscore the complexity of managing Acinetobacter infections, requiring a holistic approach in healthcare settings. The findings inform strategies for infection prevention, surveillance, and therapeutic approaches in the global effort to combat antimicrobial resistance

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Global Health Governance and Antimicrobial Resistance

Cited by 3 publications

References 46 publications

Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Bridging the gaps in the global governance of antimicrobial resistance: the UN sustainable development goals and global health security agenda

Clinical and Antimicrobial Profile of Acinetobacter Species in Critical Care Setting- An Emerging Nosocomial Bug

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