Global Hidradenitis Suppurativa COVID‐19 Registry: a registry to inform data‐driven management practices

Abstract

alveolar capillaries, 2 endothelial cells of kidney glomeruli, 3 brain blood vessels, 4 colonic mucosa 5 and skin. 6 Our immunohistochemical study represents a straightforward means of linking SARS-CoV-2 infection and endothelium.The presence of the virus in eccrine glands suggests sweat as a source of contagion, but this should be interpreted with caution. Given the similarities of SARS-CoV and SARS-CoV-2, it is worth mentioning that in a 2004 study of four autopsied patients with SARS, Ding et al. 7 found SARS-CoV nucleoprotein and RNA by immunohistochemistry and in situ hybridization, respectively, in a wide array of tissues, including sweat glands, intestine and kidney. They speculated accordingly the possibility of virus transmission through faeces, urine and sweat. A number of viruses, like hepatitis C virus, are known to replicate in sweat glands and keratinocytes; this could be investigated in sweat obtained by pilocarpine stimulation. 8Acknowledgments: We would like to thank Sandra P erez-Buira, PhD, who optimized and performed the immunohistochemical study.

Association of COVID‐19 with skin diseases and relevant biologics: a cross‐sectional study using nationwide claim data in South Korea*

“…Thus, additional research is needed to overcome racial or ethnic disparities and small sporadic reports from across the world. Dermatologists around the world can work together to build case registries to overcome the small sample sizes of dermatological patients with COVID‐19 to inform evidence‐based management practices during the COVID‐19 pandemic 41–43 . In addition, even if the skin disease itself does not increase the susceptibility to SARS‐CoV‐2 infection, in order to reduce potential exposure of dermatological patients to patients with COVID‐19, it is necessary to reduce nonurgent outpatient visits and consider telemedicine during the COVID‐19 pandemic 42,44 …”

“…Dermatologists around the world can work 12 (0Á2) 0 1Á00 Biologics TNF-a inhibitors 3 (0Á04) 0 1Á00 0 3 (0Á04) 1Á00 3 (0Á04) 0 1Á00 3 (0Á04) 0 1Á00 Etanercept 1 (0Á01) 0 1Á00 0 1 (0Á01) 1Á00 1 (0Á01) 0 1Á00 1 (0Á01) 0 1Á00 Infliximab 1 (0Á01) 0 1Á00 0 1 (0Á01) 1Á00 1 (0Á01) 0 1Á00 1 (0Á01) 0 1Á00 Adalimumab 1 (0Á01) 0 1Á00 0 1 (0Á01) 1Á00 1 (0Á01) 0 1Á00 1 (0Á01) 0 together to build case registries to overcome the small sample sizes of dermatological patients with COVID-19 to inform evidence-based management practices during the COVID-19 pandemic. [41][42][43] In addition, even if the skin disease itself does not increase the susceptibility to SARS-CoV-2 infection, in order to reduce potential exposure of dermatological patients to patients with COVID-19, it is necessary to reduce nonurgent outpatient visits and consider telemedicine during the COVID-19 pandemic. 42,44 This study showed that patients with various dermatological diseases or exposure to biologics were not particularly susceptible to COVID-19 and did not have worse outcomes of COVID-19 compared with others.…”

COVID‐19 in patients with hidradenitis suppurativa

“…There has been some debate on whether patients with HS would have an increased risk of severe COVID because of an overlap between comorbidities associated with HS and prognostic factors of COVID‐19 2 . An international registry has been developed in an attempt to collect more comprehensive data on HS severity, therapy and COVID‐19 outcomes 3 . There has also been concern regarding potential racial disparities affecting COVID outcomes 2,4 .…”

Digital Health Surveillance Strategies for Management of Coronavirus Disease 2019

“…41,42 Many medical specialties have already invested into developing COVID-19 patient registries. [43][44][45][46] Although they are useful for research, patient registries outside the EHR system have limited capacity to receive real-time data of patients. A large regional public academic health center used rapid EHR configurations to manage COVID-19 that incorporated some of the features of our effort.…”