Agent-based modeling holds great potential as an analytical tool. Agentbased models (ABMs) are, however, also vulnerable to critique, as they often employ stylized social worlds, with little connection to the actual environment in question. Given these concerns, there has been a recent call to more fully incorporate empirical data into ABMs. This article falls in this tradition, exploring the benefits of using sampled ego network data in ABMs of cultural diffusion. Thus, instead of relying on full network data, which can be difficult and costly to collect, or no empirical network data, which is convenient but not empirically grounded, we offer a middle-ground, one combining ABMs with recent work on network sampling. The main question is whether this approach is effective. We provide a test of the approach using six complete networks; the test also includes a range of diffusion models (where actors follow different rules of adoption). For each network, we take a random ego network sample and use that sample to infer the full network structure. We then run a diffusion model through the known, complete networks, as well as the inferred networks, and compare the results. The results, on the whole, are quite strong: Across all analyses, the diffusion curves based on the sampled data are very similar to the curves based on the true, complete network. This suggests that ego network sampling can, in fact, offer a practical means of incorporating empirical data into an agent-based model. Keywords: ego networks, network sampling, agent-based models, diffusion digitalcommons.unl.edu Smith & Burow in So ciolo gical Methods & Research (2018) 2 Agent-based modeling holds great promise as an analytical tool in the social sciences (Macy and Flache 2009;Sterman 2006). Agent-based models (ABMs) rely on simulation as a means of analysis, offering an alternative to traditional statistical techniques (Macy and Willer 2002;Railsback and Volker 2011). A researcher specifies a virtual world, where actors are seeded with certain characteristics and set to interact based on a system of behavioral rules; macrolevel outcomes ultimately emerge out of these individual-level interactions (De Marchi and Page 2014; Hedström and Bearman 2009;Miller and Page 2007). Agent-based modeling is a useful tool for a number of reasons (see Axtel 2000). First, ABMs offer a social laboratory of sorts, where key conditions are allowed to vary, but all else can be held constant, allowing the researcher to pinpoint plausible causal mechanisms and generate testable hypotheses (Hedström and Ylikoski 2010;Manzo 2007). 1 Second, ABMs encourage analytical clarity, as the researcher must be explicit about their assumptions and theoretical model (Manzo 2007). And third, ABMs capture aspects of social life that are difficult to represent in traditional statistical models, such as the (nonlinear) relationship between microlevel interactions and emergent collective outcomes (Bonabeau 2002;Mabry et al. 2008).The cost of an ABM is that one must typically make d...