Global oncofertility index—data gap slows progress†

Roo, Saskia F de; Rashedi, Alexandra S.; Beerendonk, C.C.M.; Anazodo, Antoinette; Man, Anne Marie de; Nelen, W.L.D.M.; Woodruff, Teresa K.

doi:10.1093/biolre/iox051

Cited by 10 publications

(2 citation statements)

References 17 publications

(20 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, female cancer patients aged 44 or younger at diagnosis make up about 13% of all newly diagnosed cases worldwide, with breast, cervical, uterine, thyroid, and ovarian cancers being the most prevalent. Because the worldwide mortality rate has declined over the past several years, prevalence and survival have increased [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

Oncofertility: insights from IVF specialists—a worldwide web-based survey analysis

Shoham

Levy‐Toledano

Leong³

et al. 2019

J Assist Reprod Genet

View full text Add to dashboard Cite

Purpose This research sought to understand IVF-physicians' knowledge of, experience with, and attitudes toward fertility preservation for cancer patients. Methods A 35-question, self-report survey request was emailed to IVF providers who were registered on the IVF-Worldwide. com network (3826 clinics). Physicians submitted responses on the IVF-Worldwide.com website. Survey results were reported as a proportion of the responding clinics. Results Survey responses were completed by 321 (8.4%) globally distributed IVF clinics, representing 299,800 IVF cycles. Of these clinics, 86.6% (278) performed fertility preservation, treating approximately 6300 patients annually. However, 18.4% of the centers reported that patients sought advice independently, without an oncologist's referral. Ovarian tissue cryopreservation was performed by 37.7% of the clinics, yet 52.6% considered the procedure experimental. IVM was performed by 16.5% of responding clinics. A majority (63.6%) of the clinics selected treatment protocols based on each patient's malignancy. Most respondents (76.3%) disagreed that fertility preservation was not yet successful enough to make it an available option. However, 44.2% believed that pregnancy rates following oocyte cryopreservation could not be determined because not enough oocyte cryopreservation patients had completed embryo transfer. Conclusions Most clinics performed fertility preservation, tailoring protocols to each patient's disease and condition. Almost 20% of patients sought advice independently, indicating that more effort is needed to encourage oncologists to refer patients. Most survey respondents believed that data was not yet available on either live birth outcomes or the best protocol for each disease. Therefore, long-term study must continue, with the establishment of interim milestones and an outcome-tracking registry.

show abstract

Section: Introductionmentioning

confidence: 99%

Oncofertility: insights from IVF specialists—a worldwide web-based survey analysis

Shoham

Levy‐Toledano

Leong³

et al. 2019

J Assist Reprod Genet

View full text Add to dashboard Cite

show abstract

“…When analyzing the quality of websites, we found moderate scores for reliability and usability. Since oncofertility is an emerging topic (de Roo et al, 2017;De Vos, Smitz, & Woodruff, 2014;Jeruss & Woodruff, 2009;Woodruff, 2010Woodruff, , 2013, this may simply reflect the initial online material can now be updated with more contemporary information. Quality may also be improved by updating the content at an appropriate time interval and citing original sources.…”

Section: Discussionmentioning

confidence: 99%

Female fertility in the cancer setting: availability and quality of online health information

et al. 2018

Self Cite

View full text Add to dashboard Cite

As cancer survival rates continue to increase, so does the relevance of starting or expanding a family after cancer, impacting quality of life. However, the option of fertility preservation is not always addressed by physicians before treatment. In the meanwhile, many patients look for health information online. Although potentially helpful in the decision-making process, the Internet could also have adverse effects for this vulnerable patient group when information is incorrect. We aimed to assess the availability and quality of information on female oncofertility on websites of (inter)national oncology, fertility and oncofertility organizations. Availability was identified using an original checklist. Quality was measured by reliability (DISCERN and LIDA instruments), usability (LIDA instrument), and readability (Flesch Kincaid Grade Level test). Of all investigated websites, 52% contained information on oncofertility, with 32% containing a stand-alone page. Of those sites, the amount of treatment options covered were equivalent between specialty sites and general fertility and oncology sites (p = 0.07). The quality of information on treatment choices was the highest for oncofertility websites. Reliability and usability did not differ significantly between websites. No websites evaluated were at the recommended 7th-8th grade reading level. Availability and quality should be improved, and high-quality resources are recommended by physicians.

show abstract