We present a general prescription for determining the global U (1) symmetries of sixdimensional superconformal field theories (6D SCFTs). We use the quiver-like gauge theory description of the tensor branch to identify candidate U (1) symmetries which can act on generalized matter. The condition that these candidate U (1)'s are free of Adler-Bell-Jackiw (ABJ) anomalies provides bottom-up constraints for U (1)'s. This agrees with the answer obtained from symmetry breaking patterns induced by Higgs branch flows. We provide numerous examples illustrating the details of this proposal. In the F-theory realization of these theories, some of these symmetries originate from deformations of non-abelian flavor symmetries localized on a component of the discriminant, while others come from an additional generator of the Mordell-Weil group. We also provide evidence that some of these global U (1)'s do not arise from gauge symmetries, as would happen in taking a decoupling limit of a model coupled to six-dimensional supergravity.There is a striking interplay between stringy extra-dimensional geometric structures and low energy effective field theories. This is particularly manifest in the context of F-theory compactifications, where intersecting seven-branes are geometrized into elliptically fibered Calabi-Yau spaces [1-3]. A prominent example illustrating the power of such methods is the recent classification of six-dimensional superconformal field theories (6D SCFTs) via Ftheory [4,5] (see also [6,7]). This provides a remarkably flexible approach to constructing 6D SCFTs which encompasses essentially all other methods (see [8][9][10][11][12][13][14][15][16][17][18][19][20][21] for a partial list of older references, references [22][23][24][25][26] for recent holographic examples, and [27] for a review).With these results in place, it is natural to ask what detailed features of 6D SCFTs can be extracted from the associated geometries. One piece of information which is readily available from an F-theory model is the tensor branch of the 6D SCFT moduli space, as this is encoded directly in terms of Kähler deformations of the base of an F-theory model. Additionally, some global symmetries correlate with the appearance of non-compact sevenbranes intersecting the localized region inhabited by a 6D SCFT. This, in tandem with field theoretic techniques, has made it possible to tightly constrain the structure of anomalies in 6D SCFTs [28][29][30][31][32][33].Even so, there are a number of outstanding open issues connected with determining the structure of global symmetries in a 6D SCFT. In what follows we exclusively focus on the case of continuous zero-form symmetries. While in many cases there is a close match between the flavor symmetries expected from geometric and field theoretic methods, there are notable examples where either the F-theory model only captures a subset of possible flavor symmetries, and conversely, where a "naïve" field theoretic analysis might at first suggest a bigger flavor symmetry than what can actually be...