Global prevalence of depression in older adults: A systematic review and meta-analysis of epidemiological surveys

Cai, Hong; Jin, Yu; Li, Rui; Zhang, Qinge; Su, Zhaohui; Ungvári, Gábor S.; Tang, Yi-Lang; Ng, Chee H.; Li, Xiaohong; Xiang, Yu‐Tao

doi:10.1016/j.ajp.2022.103417

Cited by 92 publications

(51 citation statements)

References 79 publications

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“…We observed a higher prevalence of depression in 2021 study, which was consistent with prior studies both in Korea and global areas [20,21]. These ndings may be explained by changes in the characteristics of older adults in the past decade, such as the inclusion of the baby boomer generation as old adults.…”

Section: Discussionsupporting

confidence: 90%

“…This study showed a downward trend in the prevalence of suicidal behaviors among older Korean people, although it was not statistically con rmed. This decreasing pattern has also been reported in other countries [21,28]. Korean statistics also reported a decline in the suicide rates in older adults from its peak of 81.9 per 100,000 in 2010 to 42.2 per 100,000 in 2020 [5].…”

Section: Discussionsupporting

confidence: 72%

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Ten-year differences in the prevalence and related factors of depression and suicidal behavior in Korean older adults: A comparison of representative nationwide studies for mental disorders in 2011 and 2021

Jeon,

Hahm,

Seong

et al. 2024

Preprint

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Purpose As the baby boomer generation moves into old age, the characteristics of the older population are changing. This study aimed to compare the prevalence of depression and suicidal behavior and examine the different impacts of sociodemographic risk factors based on two nationwide cross-sectional studies conducted a decade apart.Methods We compared representative samples of participants aged 60–74 years from two nationwide surveys in 2011 and 2021. Depression and suicidal behavior were assessed using the Korean version of the Composite International Diagnostic Interview, and the prevalence rates were compared according to study year and gender. We used multivariate logistic regression to determine how sociodemographic risk factors affected depression and suicidal behavior in each study period.Results The prevalence of depression in older adults was higher in 2021 than in 2011, with a notable increase among older men. The prevalence of suicidal behavior was slightly decreased but not statistically confirmed. In 2011, being female was the only risk factor for depression; however, several sociodemographic factors, including non-married, low income, and high education level, were identified as risk factors for depression in 2021. The impact of low-income status on both depression and suicidal behavior was twice as much in 2021 as it was in 2011.Conclusion The prevalence of depression has increased compared to a decade ago, especially among older men. Recently, sociodemographic risks have become more important in late-life depression and suicidal behavior. Mental health promotion for older adults needs to consider sociocultural characteristics and environmental changes.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 72%

Ten-year differences in the prevalence and related factors of depression and suicidal behavior in Korean older adults: A comparison of representative nationwide studies for mental disorders in 2011 and 2021

Jeon,

Hahm,

Seong

et al. 2024

Preprint

View full text Add to dashboard Cite

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“…The sample size was calculated using the formula N = Za 2 P (1–P)/d 2 , in which a = 0.05 and Z a = 1.96, and the estimated acceptable margin of error for proportion d was 0.05. The prevalence of depression among older population was estimated to be 35.1% based on a previous study ( 34 ). Assuming that 10% of those invited would refuse participation in this study, a sample size of at least 249 participants would be ideal.…”

Section: Methodsmentioning

confidence: 99%

Prevalence of depression and its association with quality of life in patients after pacemaker implantation during the COVID-19 pandemic: A network analysis

et al. 2023

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BackgroundThis study was designed to investigate the prevalence and predictors of depression in patients after pacemaker implantation during the COVID-19 pandemic in addition to identifying specific depressive symptoms associated with quality of life (QOL) using network analysis (NA).MethodsThis cross-sectional, observational study was conducted in China between July 1, 2021, and May 17, 2022. Descriptive analysis was used to calculate depression prevalence. Univariate analyses were used to compare differences in demographic and clinical characteristics between depressed and non-depressed patients following pacemaker implantation. Binary logistic regression analysis was used to assess factors independently associated with depression. Network analysis “expected influence,” and flow function indexes were used to identify symptoms central to the depression network of the sample and depressive symptoms that were directly associated with QOL, respectively. Network stability was examined using a case-dropping bootstrap procedure.ResultsIn total, 206 patients implanted with a pacemaker met the study entry criteria and completed the assessment. The overall prevalence of depression (PHQ-9 total score ≥ 5) was 39.92% [95% confidence interval (CI) = 29.37−42.47%]. A binary logistic regression analysis revealed that patients with depression were more likely to report a poor health status (p = 0.031), severe anxiety symptoms (p < 0.001), and fatigue (p < 0.001). In the network model for depression, “Sad mood,” “Poor Energy,” and “Guilt” were the most influential symptoms. “Fatigue” had the strongest negative association with QOL, followed by “Sad mood” and “Appetite”.ConclusionDepression is common among patients having undergone pacemaker implantation during the COVID-19 pandemic. Anxiety, central symptoms of depression (i.e., “Sad mood”, “Poor Energy”, and “Guilt”) and depressive symptoms linked to QOL (i.e., “Sad mood”, “Appetite”, and “Fatigue”) identified in this study are promising targets for interventions and preventive measures for depression in patients who have undergone pacemaker implants.

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“…In addition, numerous epidemiological studies have demonstrated that depression is more prevalent in certain populations and associated with various diseases. A meta-analysis that included 55 observational studies showed a global prevalence of depression in the elderly population of 35.1% [5]. Another recently published meta-analysis showed a global prevalence of depression of 34% in adolescents aged 10-19 years [6].…”

Section: Introductionmentioning

confidence: 99%

Association between Weight-Adjusted Waist Index and Depression in NAFLD: The Modulating Roles of Sex and BMI

Zhang,

Wang,

Xie

et al. 2024

Preprint

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Background The Weight-Adjusted Waist Index (WWI) is a novel indicator of obesity that accurately reflects body composition. However, the association between WWI and depression in patients with non-alcoholic fatty liver disease (NAFLD) remains unclear. This study aims to explore this relationship through a nationally representative cross-sectional analysis. Methods This study included adult participants diagnosed with NAFLD from NHANES 2017–2020. WWI was calculated as the waist circumference (cm) divided by the square root of body weight (kg). NAFLD diagnosis relied on vibration-controlled transient elastography (VCTE) with a controlled attenuation parameter (CAP) exceeding 248 dB/m to indicate hepatic steatosis. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9), with scores ≥ 10 indicating the presence of major depression. Results After adjusting for all covariates, a significant positive association was found between WWI and depression in NAFLD (OR = 1.725, 95% CI: 1.442–2.063, p < 0.00001), with a dose-response relationship indicated by restricted cubic spline analysis. The association was stronger in men and lean NAFLD patients. Adjusting further for BMI did not alter these findings (OR = 1.643, 95% CI: 1.357–1.989, p < 0.00001). BMI's association with depression was negated after adjusting for WWI. Conclusions WWI had a positive association with depression in NAFLD, independent of BMI. This association was more pronounced in men and lean NAFLD. These findings suggest that WWI may be a novel predictor of depression in NAFLD and potentially valuable in depression prevention.

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Global prevalence of depression in older adults: A systematic review and meta-analysis of epidemiological surveys

Cited by 92 publications

References 79 publications

Ten-year differences in the prevalence and related factors of depression and suicidal behavior in Korean older adults: A comparison of representative nationwide studies for mental disorders in 2011 and 2021

Ten-year differences in the prevalence and related factors of depression and suicidal behavior in Korean older adults: A comparison of representative nationwide studies for mental disorders in 2011 and 2021

Prevalence of depression and its association with quality of life in patients after pacemaker implantation during the COVID-19 pandemic: A network analysis

Association between Weight-Adjusted Waist Index and Depression in NAFLD: The Modulating Roles of Sex and BMI

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