Global, regional and national burden of low back pain 1990–2019: A systematic analysis of the Global Burden of Disease study 2019

Abstract

Background To comprehensively analyze the global level and trends of prevalence, incidence and years lived with disability (YLDs) for low back pain (LBP) from 1990 to 2019 by age, sex and sociodemographic index (SDI). Methods Publicly available modelled data and methods were obtained from the Global Burden of Diseases (GBD) study 2019, and used to evaluate the global burden of LBP through a systematic analysis. Results Globally, the age-standardized prevalence, incidence and YLDs rate of LBP were slightly decreased from 1990 to 2019, but the number of the prevalent cases, incident cases and YLDs had substantially increased, and LBP remains the leading cause of YLDs in 2019 worldwide. The number of prevalent cases was increased with age and peaked at the age of 45–54 years for both sexes, and the global prevalence rate was higher in females than in males and increased with age, peaking at the 80–84 age group in both sexes in 2019. Overall, a positive association between the age-standardized YLD rate and SDI was observed over the past thirty years. At the national revel, the United States, Denmark and Switzerland had the three highest levels of age-standardized prevalence, while Zambia, Zimbabwe and Canada showed the highest increase in the age-standardized prevalence during 1990–2019. Conclusions LBP is a major public health issue globally, and its burden remains high. Increasing population awareness about its risk factors and preventive measures for LBP are needed to reduce the future burden of this condition. The translational potential of this article Due to the high prevalence and heavy burden of LBP globally, it is important to update its epidemiological data. This systematic analysis provides researchers and healthcare policy makers with up-to-date, comprehensive and comparable information on global LBP burden, which is of clinical translational significance.

Injectable hydrogel with nucleus pulposus-matched viscoelastic property prevents intervertebral disc degeneration

“…The current surgical approaches for the alleviation of severe LBP, such as spinal fusion and discectomy, can barely restore the spinal biomechanics to healthy condition, and may even induce further IVDD at the initially affected spinal segment or adjacent IVDs, due to their anatomical position hardly accessible for surgical repair without mechanical damage to their surrounding tissues and original structure [ 29 ]. As a result, the demand of minimally invasive strategies to treat spinal diseases without fusion or discectomy has rapidly increased in recent years [ 30 ]. The ultimate goal of an ideal approach for treating LBP is to restore the motion and mechanical state to normal physiological conditions besides pain relief.…”

The language of all medical publications and spine publications from 1950 to 2020

“…Spinal pathology is a global issue and therefore bridging scientific knowledge across countries and languages is crucial. Low back pain is the leading cause of disability worldwide [7] , [8] , [9] , [10] . In addition, Pellise et al.…”

A Scoping Review on the Epidemiology of Chronic Low Back Pain among Adults in Sub-Saharan Africa

“…According to the Global burden of disease (GBD) 2017, the global years lived with disability (YLD) were 42.5 million (95% UI: 30.2–57.2 million) in 1990 and increased by 52.7% to 64.9 million (95% UI: 46.5–87.4 million) in 2017 [ 2 ]. In 2019, the global LBP prevalent cases were 568.4 million, with an age-standardized point-prevalence of 6972.5 per 100,000 population, and 223.5 million incidence cases with an age-standardized annual incidence of 2748.9, globally [ 3 ]. Low back pain is now the global leading cause of disability and work absenteeism, associated with huge socioeconomic burden and production loss [ 4 ].…”