2023
DOI: 10.1016/s0140-6736(23)01301-6
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Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021

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Cited by 1,132 publications
(311 citation statements)
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“…Diabetes is a serious chronic disease caused by biological abnormality of the β-cell or deficiency of insulin action, characterized by elevated blood glucose levels, and is one of the main causes of death and disability worldwide. In 2021, there were 529 million diabetics in the world (about 90% are type II diabetics), and it is predicted that this number will increase to 1.31 billion by 2050 . In order to reduce the global disease burden and alleviate pressure on healthcare systems, various strategies have made significant progress.…”
Section: Biological Activity and Health Function Advantagesmentioning
confidence: 99%
“…Diabetes is a serious chronic disease caused by biological abnormality of the β-cell or deficiency of insulin action, characterized by elevated blood glucose levels, and is one of the main causes of death and disability worldwide. In 2021, there were 529 million diabetics in the world (about 90% are type II diabetics), and it is predicted that this number will increase to 1.31 billion by 2050 . In order to reduce the global disease burden and alleviate pressure on healthcare systems, various strategies have made significant progress.…”
Section: Biological Activity and Health Function Advantagesmentioning
confidence: 99%
“…Chronic kidney disease (CKD) associated with type 2 diabetes (T2D) is a leading cause of end-stage kidney disease worldwide, whose incidence is projected to increase over the next decades. 1 The preclinical stage of diabetic nephropathy is characterised by an abnormal elevation in glomerular filtration rate (GFR), defined as glomerular hyperfiltration, which can contribute to kidney damage progression and albuminuria by increasing capillary pressure and tensile stress. 2 Glomerular hyperfiltration has been associated with worse kidney [3][4][5] and cardiovascular outcomes 6,7 and increased cardiovascular and allcause mortality, 5,8,9 which are only partly explained by its close association with poor glycaemic control, obesity, hypertension, and dyslipidemia.…”
Section: Introductionmentioning
confidence: 99%
“…Diabetes mellitus has become the most critical health concern, with a global burden reaching over 537 million people in 2021, and is projected to exceed one billion people by 2050 (International Diabetes Federation, 2021;Ong et al, 2023). Turkey ranks first among European countries, with a prevalence rate of 15.9% in the adult population (International Diabetes Federation, 2021).…”
Section: Introductionmentioning
confidence: 99%