Global, regional, and national prevalence and disability-adjusted life-years for endometriosis in 204 countries and territories, 1990– 2019: findings from a global burden of disease study

Abstract

Introduction: This study aimed to analyze the worldwide, regional, and intra-country burden of heteropathy and its trends from 1990 to 2019, utilizing the latest data and improved methodologies from GBD 2019. Methods: We utilized the Global Health Data Exchange Query tool, Global Burden of Disease (GBD), to analyze endometriosis in prevalence numbers, age-standardized prevalence rates (ASPR), and disability-adjusted life-years (DALYs) from 1990 to 2019 in 204 countries and regions. Additionally, this study investigated the impacts of period, age, and cohort on the prevalence and DALYs of endometriosis from the global perspective and in the five sociodemographic index (SDI) regions. Results: Among the 21 regions, the most significant reduction in the prevalence of heterosis between 1990 and 2019 occurred in Central Latin America. In 204 countries, the most pronounced decline was observed in Guatemala. At the SDI level, with the increase of SDI, the ASPR of endometriosis in all regions worldwide showed an overall decreasing trend. The prevalence of endometriosis peaked between the ages of 25 and 29. Discussion: The findings of this study reflect the temporal and spatial tendency of the burden of endometriosis during the study period and provide an epidemiological basis for reducing endometriosis.