The outbreak of SARS CoV-2 (COVID-19) has posed a serious threat to human beings, society, and economic activities all over the world. Worldwide rigorous containment measures for limiting the spread of the virus have several beneficial environmental implications due to decreased anthropogenic emissions and air pollutants, which provide a unique opportunity to understand and quantify the human impact on atmospheric environment. In the present study, the associated changes in Land Surface Temperature (LST), aerosol, and atmospheric water vapor content were investigated over highly COVID-19 impacted areas, namely, Europe and North America. The key findings revealed a large-scale negative standardized LST anomaly during nighttime across Europe (–0.11°C to –2.6°C), USA (–0.70°C) and Canada (–0.27°C) in March–May of the pandemic year 2020 compared to the mean of 2015–2019, which can be partly ascribed to the lockdown effect. The reduced LST was corroborated with the negative anomaly of air temperature measured at meteorological stations (i.e. –0.46°C to –0.96°C). A larger decrease in nighttime LST was also seen in urban areas (by ∼1–2°C) compared to rural landscapes, which suggests a weakness of the urban heat island effect during the lockdown period due to large decrease in absorbing aerosols and air pollutants. On the contrary, daytime LST increased over most parts of Europe due to less attenuation of solar radiation by atmospheric aerosols. Synoptic meteorological variability and several surface-related factors may mask these changes and significantly affect the variations in LST, aerosols and water vapour content. The changes in LST may be a temporary phenomenon during the lockdown but provides an excellent opportunity to investigate the effects of various forcing controlling factors in urban microclimate and a strong evidence base for potential environmental benefits through urban planning and policy implementation.