2017
DOI: 10.3201/eid2308.161138
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Global Spread of Norovirus GII.17 Kawasaki 308, 2014–2016

Abstract: Analysis of complete capsid sequences of the emerging norovirus GII.17 Kawasaki 308 from 13 countries demonstrated that they originated from a single haplotype since the initial emergence in China in late 2014. Global spread of a sublineage SL2 was identified. A new sublineage SL3 emerged in China in 2016.

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Cited by 73 publications
(49 citation statements)
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“…The epidemic strains were GII.P17‐GII.17 variants represented by Kawasaki308_2015 with a novel RdRp genotype produced by recombination and genetic changes in the capsid gene . The acquisition of a novel RdRp would have caused changes in the replication ability of the virus, affecting its propagation and evolutionary rate.…”
Section: Discussionsupporting
confidence: 70%
See 1 more Smart Citation
“…The epidemic strains were GII.P17‐GII.17 variants represented by Kawasaki308_2015 with a novel RdRp genotype produced by recombination and genetic changes in the capsid gene . The acquisition of a novel RdRp would have caused changes in the replication ability of the virus, affecting its propagation and evolutionary rate.…”
Section: Discussionsupporting
confidence: 70%
“…It remains unclear why NoV GII.17 suddenly emerged and quickly spread in that particular season. However, previous papers and the present study suggest that this NoV GII.17 epidemic was affected by several factors, including pathogens, hosts, and other environmental factors.…”
Section: Discussionmentioning
confidence: 99%
“…In our present study, we provide further support for their hypotheses. Thus, the GII.17 noroviruses may represent a new target that needs to be considered for future vaccine strategies against noroviruses (24).…”
Section: Discussionmentioning
confidence: 99%
“…For example, GII.3 and not GII.4 viruses were the most prevalent genotype for 34 years (1974–1991) in children seeking care at the Children's Hospital in Washington, USA [Bok et al, 2009]. Also, the global spread of norovirus GII.17 between 2014 and 2016 have raised concern about the potential of this emerging genotype to replace GII.4[Chan et al, 2017]. …”
Section: Discusionmentioning
confidence: 99%