Global tendencies and frontier topics in hemodynamics research of intracranial aneurysms: a bibliometric analysis from 1999 to 2022

Abstract

Background: Hemodynamics plays a crucial role in the initiation, enlargement, and rupture of intracranial aneurysms (IAs). This bibliometric analysis aimed to map the knowledge network of IA hemodynamic research.Methods: Studies on hemodynamics in IAs published from 1999 to 2022 were retrieved from the Web of Science Core Collection (WoSCC). The contributions of countries, institutions, authors, and journals were identified using VOSviewer, Scimago Graphica, and Microsoft Excel. Tendencies, frontier topics, and knowledge networks were analyzed and visualized using VOSviewer and CiteSpace.Results: We identified 2,319 publications on hemodynamics in IAs. The annual number of publications exhibited an overall increasing trend. Among these, the United States, Japan, and China were the three major contributing countries. Capital Medical University, State University of New York (SUNY) Buffalo University, and George Mason University were the three most productive institutions. Meng H ranked first among authors regarding the number of articles and citations, while Cebral JR was first among co-cited authors. The American Journal of Neuroradiology was the top journal in terms of the number of publications, citations, and co-citations. In addition, the research topics can be divided into three clusters: hemodynamics itself, the relationship of hemodynamics with IA rupture, and the relationship of hemodynamics with IA treatment. The frontier directions included flow diverters, complications, morphology, prediction, recanalization, and four-dimensional flow magnetic resonance imaging (4D flow MRI).Conclusion: This study drew a knowledge map of the top countries, institutions, authors, publications, and journals on IA hemodynamics over the past 2 decades. The current and future hotspots of IA hemodynamics mainly include hemodynamics itself (4D flow MRI), its relationship with IA rupture (morphology and prediction), and its relationship with IA treatment (flow diverters, complications, and recanalization).

Effect of Siphon Morphology on the Risk of C7 Segment Aneurysm Formation

“…Early studies have identified relationships between vascular tortuosity and aneurysms [ 19 ], including thoracic aneurysms [ 20 ], coronary aneurysms [ 21 ], and splenic artery aneurysms [ 22 ]. Intracranial aneurysms can be affected by the tortuosity of extracranial or intracranial vessels [ 23 , 24 ].…”

“…The hemodynamic mechanism underlying the development of vascular tortuosity in aneurysms remains unclear. A previous study revealed that the high bend curvature of siphons causes dynamic fluctuations in the WSS and WSSG, which can result in damage to the artery wall and the formation of aneurysms in curved sections [ 9 , 19 ]. We used CFD analysis to identify aneurysm-related hemodynamics in the distal section of the siphon.…”