Global Trends in Research of Macrophages Associated With Acute Lung Injury Over Past 10 Years: A Bibliometric Analysis

Abstract

Acute lung injury (ALI) is an intractable disorder associated with macrophages. This bibliometric analysis was applied to identify the characteristics of global scientific output, the hotspots, and frontiers about macrophages in ALI over the past 10 years. We retrieved publications published from 2011 to 2020 and their recorded information from Science Citation Index Expanded (SCI-expanded) of Web of Science Core Collection (WoSCC). Bibliometrix package was used to analyze bibliometric indicators, and the VOSviewer was used to visualize the trend and hotspots of researches on macrophages in ALI. Altogether, 2,632 original articles were reviewed, and the results showed that the annual number of publications (Np) concerning the role of macrophages in ALI kept increasing over the past 10 years. China produced the most papers, the number of citations (Nc) and H-index of the USA ranked first. Shanghai Jiaotong University and INT IMMUNOPHARMACOL were the most prolific affiliation and journal, respectively. Papers published by Matute-Bello G in 2011 had the highest local citation score (LCS). Recently, the keywords “NLRP3” and “extracellular vesicles” appeared most frequently. Besides, researches on COVID-19–induced ALI related to macrophages seemed to be the hotspot recently. This bibliometric study revealed that publications related to macrophages in ALI tend to increase continuously. China was a big producer and the USA was an influential country in this field. Most studies were mainly centered on basic researches in the past decade, and pathways associated with the regulatory role of macrophages in inhibiting and attenuating ALI have become the focus of attention in more recent studies. What is more, our bibliometric analysis showed that macrophages play an important role in COVID-19–induced ALI and may be a target for the treatment of COVID-19.

The Research Landscape of Ferroptosis in Cancer: A Bibliometric Analysis

“…The term bibliometric was coined in 1969 by Alan Pritchard ( Pritchard, 1969 ). Bibliometric analysis is a powerful tool that uses literature metrics or indicators to quantitively measure the research performance in a certain field ( Deng et al, 2020 ; Wang et al, 2021 ). CiteSpace and VOSviewer are two commonly used visualizing processing tools for bibliometric analysis ( Moral-Muñoz et al, 2020 ).…”

Trends in the Research Into Immune Checkpoint Blockade by Anti-PD1/PDL1 Antibodies in Cancer Immunotherapy: A Bibliometric Study

“…Several related documents were found in our datasets due to the attention of researchers to PD1/PDL1 expression in various kinds of cells ( Brummelman et al, 2018 ; Penter et al, 2019 ). A recent bibliometric study focused on single cell sequencing technologies and suggested its applications in immunology would be the next research hotspot ( Wang et al, 2021 ). We found that in single cell sequencing had been applied in the patients with anti-PD1/PDL1 therapy to figure out the changes of cell subsets after treatments and differences between responders and non-responders, which could contribute to predict prognosis, select suitable therapy strategy and monitor the condition of diseases ( Bassez et al, 2021 ; Gohil et al, 2021 ).…”

“…Local citation score (LCS) represents the number of times that an article has been referenced in the current dataset, therefore, a high LCS indicated the importance of the article in the field. Besides, the global citation score (GCS) was also been calculated, which is the number of times the article has been cited by all documents in the entire WoSCC database, and it covers the influence of the article on other areas ( Wang et al, 2021 ). The citation thresholds were set to identify the number of influential documents and we also concerned the citations per year since their publication to define the references with citation bursts ( Mulet-Forteza et al, 2019a ; Merigó et al, 2019 ).…”

Antimicrobial Stewardship in Surgery: A Literature Bibliometric Analysis

“…We focused on searching for articles in the WoS core collection database using comprehensive search strategy to cover more publications. In our study, search terms included “antimicrobial/antibiotic stewardship”, “antimicrobial/antibiotic management”, “antimicrobial/antibiotic management strategies”, “antimicrobial/antibiotic stewardship programme” and “surgery/surgical”, according to previous studies ( 7 , 10 , 11 ). Additionally, language was restricted to English, and document type was restricted to original articles published from January 1, 2011 to December 31, 2020.…”